Infectious diseases A-Z: Flu vaccine is a good match

The flu vaccine is a good match for the 2019-2020 flu season, reports the Centers for Disease Control and Prevention (CDC). Efficacy of the vaccine is estimated to be 45% so far this season. The CDC says the vaccine was even better for kids, providing substantial protection at 55% efficacy among children and adolescents aged 6 months to-17. In comparison, […]

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Zika vaccine induces potent Zika and dengue cross-neutralizing antibodies

A new study led by scientists at the Walter Reed Army Institute of Research has shown for the first time that a single dose of an experimental Zika vaccine in a dengue-experienced individual can boost pre-existing flavivirus immunity and elicit protective cross-neutralizing antibody responses against both Zika and dengue viruses. Findings were published today in Nature Medicine. Researchers analyzed the […]

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FDA gives first Ebola vaccine for adults the green light

(HealthDay)—The first Ebola vaccine approved by the U.S. Food and Drug Administration is a single-dose injection called Ervebo. The vaccine from Merck & Co. is approved to protect against the Zaire ebolavirus in people ages 18 years and older. In the United States, Ebola infections are rare. Confirmed cases have involved people in other countries who became infected and then […]

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Rectal microbes influence effectiveness of HIV vaccine

Microbes living in the rectum could make a difference to the effectiveness of experimental HIV vaccines, according to researchers at the University of California, Davis. The work is published Dec. 11 in the journal mSphere. Evidence from human and animal studies with other vaccines suggests that Lactobacillus supplements can boost production of antibodies, while treatment with antibiotics can hamper beneficial […]

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Initial reports suggest new dengue vaccine safer than prior vaccines

A team of researchers at Takeda Vaccines has announced the results of the first phase of trial testing a new vaccine to prevent dengue infections. In their paper published in The New England Journal of Medicine, they outline their trial and how well the drug is working in test cases. The dengue virus infects hundreds of millions of people every […]

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Researchers partner in vaccine project to tackle major killer of African children

A team of University of Otago researchers is part of a major new international vaccine research project to help tackle devastating Salmonella bloodstream infections which are killing thousands of people in sub-Saharan Africa each year. The recently-launched Vacc-iNTS research project aims to advance the clinical development of an innovative vaccine against invasive non-typhoidal salmonellosis. This is an emerging neglected infectious […]

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Uganda begins largest trial of experimental Ebola vaccine

Researchers in Uganda are launching the largest-ever trial of an experimental Ebola vaccine that is expected to be deployed in neighboring Congo, where a deadly outbreak has killed over 1,800 people. The trial of the Janssen Pharmaceuticals vaccine involves up to 800 people and is supported by Doctors without Borders and the London School of Hygiene and Tropical Medicine. Pontiano […]

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Conspiracy theories and fear of needles contribute to vaccine hesitancy for many parents

Over 1,160 cases of measles have been confirmed in the U.S. in 2019. That is more measles cases in just seven months than any full year this decade, and, more problematically, more than all U.S. measles cases from 2010-2013 and 2015-2017 combined. Lawmakers in some states, such as Washington and New York, are already stepping in to combat the outbreak […]

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