Eli Lilly ends antibody trial early after failed to help in recovery

Eli Lilly ends paused trial of antibody drug and remdesivir after the NIH found the combo failed to help recovery of hospitalized patients  Eli Lilly & Co and the National Institues of Health announced they are ending a clinical trial of antibody drug The study was looking at a combination of the antibody, LY-CoV555, and remdesivir as a treatment for hospitalized coronavirus […]

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Scientists to Infect Volunteers With COVID-19 in Challenge Trial

TUESDAY, Oct. 20, 2020 — British scientists are infecting healthy volunteers with COVID-19, in hopes of speeding up vaccine development, TheWashington Postreported Tuesday. Led by scientists at Imperial College London, people in this challenge trial will be guaranteed treatment if they become ill. The United States says human challenge trials might be too risky or unnecessary. But for the British, […]

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NIH Launches Trial of Antibody Drugs Against COVID-19

WEDNESDAY, Oct. 14, 2020 — A study to assess whether certain approved or experimental drugs are effective against COVID-19 and warrant testing in large clinical trials has been launched by the U.S. National Institutes of Health (NIH). The research will largely focus on monoclonal antibody medications. These types of drugs garnered headlines last week as President Donald Trump credited one […]

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Medical trial meets one primary endpoint in heart failure with preserved ejection fraction

Sacubitril/valsartan reduces NT-proBNP, a biomarker predictive of long-term clinical outcomes in heart failure, but does not improve functional capacity compared to individualized background therapy in patients with heart failure with preserved ejection fraction. That’s the main finding of the PARALLAX trial presented in a Hot Line session today at ESC Congress 2020. Heart failure with preserved ejection fraction (HFpEF) affects […]

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UK trial will tell us if fighting off coronavirus gives you immunity

UK trial will tell us if fighting off coronavirus gives you immunity… and it could be the key to ending lockdown Some 20,000 antibody testing kits are being sent to homes across the country 5,000 tests have gone out and 15,000 more will be distributed in coming days World-renowned epidemiologist Professor Sir Rory Collins is leading the trial  Here’s how […]

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First clinical trial with genetically modified malaria vaccine completed

In an innovative study, Radboudumc and LUMC jointly tested a candidate vaccine based on a genetically weakened malaria parasite. The results of this clinical trial, published in Science Translational Medicine, show that the vaccine is safe and elicits a defense response against a malaria infection. Malaria is a major infectious disease, caused by a parasite with a complicated life cycle […]

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