FDA Approves Trodelvy, the First Treatment for Metastatic Triple-Negative Breast Cancer Shown to Improve Progression-Free Survival and Overall Survival

FOSTER CITY, Calif.–(BUSINESS WIRE)–Apr. 7, 2021– Gilead Sciences, Inc. (Nasdaq: GILD) today announced that the U.S. Food and Drug Administration (FDA) has granted full approval to Trodelvy® (sacituzumab govitecan-hziy) for adult patients with unresectable locally advanced or metastatic triple-negative breast cancer (TNBC) who have received two or more prior systemic therapies, at least one of them for metastatic disease. The approval is supported by data […]

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Researchers discover a novel cell-to-cell communication network that helps tumors regrow following treatment

In the fight against cancers, activating mutations in the RAS family of genes stand in the way of finding viable treatment options. Now, scientists at the University of Missouri and Yale University have discovered that one of these mutations—oncogenic RAS or RASV12—is also responsible for the regrowth of cancer cells following genotoxic therapy treatment, or drugs that cause damage to […]

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Addiction treatment centers using electronic health records less and may hinder care

Despite their existence for decades, electronic health records—digitized patient information and medical histories available instantly and securely to authorized users—are not commonly used by many addiction and substance use disorder treatment facilities in the United States. Now, a recent study by Johns Hopkins Medicine researchers suggests why this is happening. It also describes how not using this technology may hinder […]

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Racial, ethnic disparities found in diagnosis, treatment of ADHD

(HealthDay)—There are racial and ethnic disparities evident in the diagnosis and treatment of attention-deficit/hyperactivity disorder (ADHD), according to a study published online March 1 in JAMA Network Open. Yu Shi, M.D., M.P.H., from the Mayo Clinic in Rochester, Minnesota, and colleagues explored differences in rates of diagnosis and treatment of ADHD among children by race and ethnicity using insurance claims […]

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Financial incentives for hospitals boost rapid changes to opioid use disorder treatment

Hospital emergency departments (EDs) not only care for patients with overdose and other complications from opioid use, but they also serve as vital touch points to engage patients into longer-term treatment. After an overdose, patients are at risk for repeat overdose and death. Pennsylvania is unique in establishing a voluntary incentive program to improve the rate at which patients with […]

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Research identifies obesity and infection link, as well as treatment found on healthy human skin

The list of diseases and conditions complicated by obesity is a long one; it includes heart disease, cancer, diabetes and impaired wound healing, as well as skin infections. It is not always clear, however, in what way this complication is caused. New research from the School of Pharmaceutical Science at Xiamen University and the Gallo Lab at UC San Diego […]

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Transplant patients may not need steroid treatment in the long run

Long-term use of a medication used to treat kidney transplant patients may not be necessary in individuals with low-to-moderate risk of organ rejection, according to the results of a study led by a University of Cincinnati transplant researcher. The randomized clinical trial of 385 patients on immunosuppressive drugs tacrolimus and mycophenolate examined whether use of these medicines called corticosteroids could […]

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Fatty liver disease: Itchy skin could indicate your risk of the dangerous disease

NHS Choices: Liver Disease When you subscribe we will use the information you provide to send you these newsletters.Sometimes they’ll include recommendations for other related newsletters or services we offer.Our Privacy Notice explains more about how we use your data, and your rights.You can unsubscribe at any time. The liver is the body’s largest organ. It breaks down fats, detoxifies […]

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Nixing bone cancer fuel supply offers new treatment approach, mouse study suggests

An innovative approach to treating bone tumors—starving cancer cells of the energy they need to grow—could one day provide an alternative to a commonly used chemotherapy drug without the risk of severe side effects, suggests a new study from Washington University School of Medicine in St. Louis. Studying human cancer cells and mice, the researchers said that a two-drug combination […]

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Statins may protect the heart from chemotherapy treatment of early breast cancer

Statins, common cholesterol-lowering medications, may protect women’s hearts from damage caused during chemotherapy for early-stage breast cancer, according to new research published today in the Journal of the American Heart Association. “Two types of cancer medications, anthracyclines and trastuzumab, are effective treatments for many women with breast cancer, however, the risk of heart muscle damage has limited their use, particularly […]

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