Experimental medication to prevent heart disease may treat chemo-resistant ovarian cancer

Most ovarian cancer starts in fallopian tubes. Then it sloughs from its site of origin and floats around in fluid until finding new sites of attachment. It’s not easy for cancer cells to survive away from their moorings. Observations by ovarian cancer doctors at University of Colorado Cancer Center and elsewhere hint at how they might do it: These doctors […]

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Old drugs might treat COVID-19—so we’re using pieces of coronavirus to find out

Why don’t we have drugs to treat COVID-19 and how long will it take to develop them? SARS-CoV-2—the coronavirus that causes the disease COVID-19—is completely new and attacks cells in a novel way. Every virus is different and so are the drugs used to treat them. That’s why there wasn’t a drug ready to tackle the new coronavirus that only […]

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It’s taking too long to treat rural Aussies who have a stroke

Addressing inequity between metropolitan and regional acute stroke care requires attention to each component of regional workflow, according to the authors of a Perspective published in the Medical Journal of Australia. About 56 000 strokes occur in Australia annually at an estimated economic cost of $5 billion per year; in regional Australia strokes occur at a rate of 250 per […]

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Using gene therapy to treat chronic traumatic encephalopathy

A new study shows the feasibility of using gene therapy to treat the progressive neurodegenerative disorder chronic traumatic encephalopathy (CTE). The study, which demonstrated the effectiveness of direct delivery of gene therapy into the brain of a mouse model of CTE, is published in Human Gene Therapy. Ronald Crystal and colleagues from Weill Cornell Medical College, New York, NY, coauthored […]

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Pediatric hematologists introduce a novel way to treat pediatric hemophilia A patients

An innovative way to treat pediatric hemophilia A patients using a combination approach has seen early success at the Aflac Cancer and Blood Disorders Center of Children’s Healthcare of Atlanta, with researchers from Emory University School of Medicine. Now known as the Atlanta Protocol, in a nod to where the approach was developed, the new method involves treating patients with […]

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Laboratory studies identify a potential way to treat human cancers with ARID1A mutations

A new study shows that tumor cells depleted of ARID1A—a protein that acts as a cancer suppressor—become highly sensitive to anticancer poly ADP ribose polymerase (PARP) inhibitor drugs after radiation treatment. The research, led by Johns Hopkins Kimmel Cancer Center researchers, could advance efforts to treat many human cancers with loss of ARID1A that are resistant to current standard treatments, […]

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Study shows widespread global implementation of WHO’s ‘Treat All’ HIV recommendation

A new study published in the Journal of the International AIDS Society shows that the World Health Organization’s (WHO) 2015 recommendation for immediate treatment of all people living with HIV has become the standard of care across HIV clinics in countries around the world. While most countries have adopted the WHO’s “Treat All” recommendation, the extent to which these guidelines […]

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