Point-of-care biomarker assay for traumatic brain injury

Intracranial abnormalities on CT scan in patients with traumatic brain injury (TBI) can be predicted by glial fibrillary acidic protein (GFAP) levels in the blood. These interim findings from the TRACK-TBI study are published in the peer-reviewed Journal of Neurotrauma. GFAP’s diagnostic performance was significantly better than that of the S100B biomarker, to which it was compared. S100B is approved […]

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Visits to the dentist can evoke memories of traumatic sexual abuse

The defencelessness experienced while sitting in the dentist’s chair can prompt memories of sexual abuse, finds endodontist Eva Wolf in her new study. She has interviewed 13 people, who had such experiences, and found many are scared and avoid going to the dentist, do not show up for scheduled appointments, or leave ongoing treatment. “It is very clear that the […]

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Stress overload and pain common among patients with traumatic brain injury

Traumatic brain injury (TBI) is a leading cause of death and disability. Post-injury distress is common, with many individuals experiencing chronic anxiety and depressive symptoms as well as chronic pain. In this collection of articles in the journal NeuroRehabilitation, experts report on findings that shed light on the relationship between stress and pain following a TBI and implications for rehabilitation. […]

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Traumatic childhood increases lifelong risk for heart disease, early death

Exposure to trauma and other adverse experiences during childhood increases lifelong risk for cardiovascular disease and death, regardless of a person’s health during young adulthood, new research shows. The study, published Tuesday in the Journal of the American Heart Association, found children who experienced severe adversity—such as verbal, physical or emotional abuse or living with drug or alcohol abusers—were 50% […]

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Using gene therapy to treat chronic traumatic encephalopathy

A new study shows the feasibility of using gene therapy to treat the progressive neurodegenerative disorder chronic traumatic encephalopathy (CTE). The study, which demonstrated the effectiveness of direct delivery of gene therapy into the brain of a mouse model of CTE, is published in Human Gene Therapy. Ronald Crystal and colleagues from Weill Cornell Medical College, New York, NY, coauthored […]

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