Researchers identify immune cells that contribute to transplant rejection

Non-circulating memory T cells, whose main function is to provide local protection against re-infection, contribute to chronic transplant rejection, University of Pittsburgh School of Medicine researchers reveal in a paper published today in Science Immunology. The scientists show that these “tissue-resident memory T cells” are harmful in situations where antigens that the cells recognize are present in the body for […]

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Transplant patients may not need steroid treatment in the long run

Long-term use of a medication used to treat kidney transplant patients may not be necessary in individuals with low-to-moderate risk of organ rejection, according to the results of a study led by a University of Cincinnati transplant researcher. The randomized clinical trial of 385 patients on immunosuppressive drugs tacrolimus and mycophenolate examined whether use of these medicines called corticosteroids could […]

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Circulating tumor DNA indicates risk of relapse after transplant in DLBCL patients

Many patients with diffuse large B-cell lymphoma (DLBCL) can be cured by a transplant using their own blood-forming stem cells, but as many as half eventually relapse. New research led by Dana-Farber Cancer Institute scientists suggests that patients whose blood or stem cell samples harbor tumor DNA are likely to relapse. The findings, presented today at the virtual 62nd American […]

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COVID-19 patient didn't recognize body after double transplant

Dr. Siegel on race to treat coronavirus symptoms Fox News medical contributor Dr. Marc Siegel on what can be done to protect people before a vaccine is approved. A Chicago woman who last month became the nation's first COVID-19 patient to undergo a double lung transplant said Thursday that she woke up days later, unaware about the surgery and unable […]

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Study finds new option for liver transplant patients

A drug commonly used to treat both asthma and inflammatory bowel disease, budesonide, may also be useful as an anti-organ rejection medication for liver transplant patients leading to fewer serious side effects than the most commonly used therapy, according to a University of Cincinnati researcher. Dr. Khurram Bari, an associate professor in the UC Division of Digestive Diseases, explains the […]

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Mum lost twin babies and needed organ transplant because of rare condition

But after making the brave decision to try for another baby with her now husband Max, 30,  she fell pregnant with Ava following a year wait. Louise wasn’t convinced little Ava, who is now one, would be born alive until being welcomed into the world on March 20, 2018. She said: ‘I never thought I would have another child. When […]

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