Synthetic tissue model with blood vessels developed

Using lab-created tissue to heal or replace damaged organs is one of the great visions for the future of medicine. Synthetic materials could be suitable as scaffolding for tissue because, unlike natural tissues, they remain stable in the organism long enough for the body to form new natural structures. A fundamental requirement for functional tissue is that blood vessels must […]

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First lab-grown mini-thyroids use patients’ own tissue

Hormones produced by the thyroid gland are essential regulators of organ function. The absence of these hormones either through thyroid dysfunction due to, for example, irradiation, thyroid cancer or autoimmune disease or thyroidectomy leads to symptoms like fatigue, feeling cold, constipation, and weight gain. Hypothyroidism is estimated to affect up to 11% of the global population. Although hypothyroidism can be […]

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Pregnant Jamie Otis Shares 'Concerning' News About Possibly Cancerous Tissue

Jamie Otis doesn’t know “whether to worry or not” after receiving “concerning news” from her doctor. “I went to the doc and heard my pap was bad & I have HPV,” the Bachelor alum, 33, captioned a Wednesday, December 4, Instagram upload. “Although it sounds like an STD and I should freak the F out, I know this is somewhat […]

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Cell family trees tracked to discover their role in tissue scarring and liver disease

Researchers have discovered that a key cell type involved in liver injury and cancer consists of two cellular families with different origins and functions. The research by academics from the Universities of Edinburgh and Bristol and funded by the Wellcome Trust and Medical Research Council, is published today [Tuesday 15 October] in Nature Communications. The distinguishing feature of these families—whether […]

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New evidence shows cytotoxic T cells can identify, invade, and destroy targets of large mass like T. gondii tissue cysts

CD8+ cytotoxic T lymphocytes can kill host cells infected with various microorganisms as well as single individual cancer cells through direct cell-to-cell contact, but their ability to destroy a target of large mass remains unexplored. A study in The American Journal of Pathology provided novel evidence on the capability of the immune system to eliminate large parasite-filled cysts associated with […]

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How pathogens are controlled when tissue is deprived of adequate oxygen supply

Infected tissue has a low concentration of oxygen. The body’s standard immune mechanisms, which rely on oxygen, can then only function to a limited extent. How does the immune system nevertheless manage to control bacteria under such conditions? The working groups led by PD Dr. Anja Lührmann and Prof. Dr. Jonathan Jantsch have investigated this question in collaboration with other […]

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The ‘wrong’ connective tissue cells signal worse prognosis for breast cancer patients

In certain forms of cancer, connective tissue forms around and within the tumour. One previously unproven theory is that there are several different types of connective tissue cells with different functions, which affect the development of the tumour in different ways. Now, a research team at Lund University in Sweden has identified three different types of connective tissue cells. In […]

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