Researchers discover a novel cell-to-cell communication network that helps tumors regrow following treatment

In the fight against cancers, activating mutations in the RAS family of genes stand in the way of finding viable treatment options. Now, scientists at the University of Missouri and Yale University have discovered that one of these mutations—oncogenic RAS or RASV12—is also responsible for the regrowth of cancer cells following genotoxic therapy treatment, or drugs that cause damage to […]

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Scientists develop diagnostic test that can detect the virus that causes COVID-19 even when it mutates

A team of scientists led by Nanyang Technological University, Singapore (NTU Singapore) has developed a diagnostic test that can detect the virus that causes COVID-19 even after it has gone through mutations. Called the VaNGuard (Variant Nucleotide Guard) test, it makes use of a gene-editing tool known as CRISPR, which is used widely in scientific research to alter DNA sequences […]

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Researchers identify immune cells that contribute to transplant rejection

Non-circulating memory T cells, whose main function is to provide local protection against re-infection, contribute to chronic transplant rejection, University of Pittsburgh School of Medicine researchers reveal in a paper published today in Science Immunology. The scientists show that these “tissue-resident memory T cells” are harmful in situations where antigens that the cells recognize are present in the body for […]

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Scientists identify genetic pathway that suppresses Lou Gehrig’s Disease

Professor Chunghun Lim and his research team in the Department of Biological Sciences unveiled a neuroprotective pathway that suppresses Lou Gehrig’s Disease (ALS). Nucleocytoplasmic transport (NCT) defects have been implicated in neurodegenerative diseases, such as C9ORF72-associated amyotrophic lateral sclerosis and frontotemporal dementia (C9-ALS/FTD). In this study, the research team has identified a neuroprotective pathway of like-Sm protein 12 (LSM12) and […]

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8 Types of Rashes That Can Be a Sign of COVID-19

Usually, this type of rash is one that lasts a long time—sometimes, it's even permanent. But as Health previously reported, dermatologists are seeing transient livedo reticularis in patients with COVID-19, meaning the rash comes and goes. The rash presents itself as tiny purple, red, or brown spots that one may mistake for bruising under the skin. According to Dr. Bataille and […]

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Researchers identify muscle factor that controls fat metabolism

Metabolic diseases, such as obesity and type 2 diabetes, have risen to epidemic proportions in the U.S. and occur in about 30 percent of the population. Skeletal muscle plays a prominent role in controlling the body’s glucose levels, which is important for the development of metabolic diseases like diabetes. In a recent study, published in The Journal of Clinical Investigation, […]

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Age groups that sustain resurging COVID-19 epidemics in the United States

As of October 2020, individuals aged 20-49 were the only groups sustaining COVID-19 transmission with reproduction numbers well above 1 in the US, according to the latest publication in Science today by the Imperial College COVID-19 Response team. Following initial declines, numbers of COVID-19 cases started to rise again halfway through 2020 in the United States and Europe. In September […]

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