Depression, tau deposits seen in subset of middle-aged persons

Middle-aged people with depressive symptoms who carry a genetic variation called apolipoprotein (APOE) ε4 may be more at risk to develop tau protein accumulations in the brain’s emotion- and memory-controlling regions, a new study by researchers from The University of Texas Health Science Center at San Antonio (UT Health San Antonio) and collaborating institutions suggests. The Journal of Alzheimer’s Disease […]

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Tau protein changes correlate with Alzheimer’s disease dementia stage

Research into Alzheimer’s disease has long focused on understanding the role of two key proteins, beta amyloid and the tau protein. Found in tangles in patients’ brain tissue, a pathological form of the tau protein contributes to propagating the disease in the brain. In new research from their joint laboratory, Judith Steen, Ph.D., and Hanno Steen, Ph.D. show for the […]

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Insight into Alzheimer’s early stages provides clues to treatment strategies

Alzheimer’s disease is the most common form of dementia, affecting more than 5 million people in the U.S., but doctors have limited advice on how to protect against it. The disease develops silently in the brain for two decades or more before people begin showing the characteristic signs of forgetfulness and confusion. Understanding that silent phase could be key to […]

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