Single-dose of BNT162b2 vaccine may not be protective without prior SARS-CoV-2 infection

Vaccine rollouts in many countries are bringing hope that the coronavirus disease 2019 (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), will come to an end in the foreseeable future. Several vaccines have shown high protective efficacy against SARS-CoV-2 infection or severe disease. Study: Effect of previous SARS-CoV-2 infection on humoral and T-cell responses to single-dose […]

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Antibody and T cell response to SARS-CoV-2 persist up to 8 months: Study of Ski Resort Ischgl

The first instance of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak in Austria was observed in the Ski resort Ischgl in early March 2020. Later, the virus spread across Austria and other countries in Northern Europe. Researchers conducted a cross-sectional study to gauge the seroprevalence of SARS-CoV-2 in the population, as measured in the blood serum. They found […]

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HSE researchers discover genetic predisposition to COVID-19 severity

HSE University researchers have become the first in the world to discover genetic predisposition to severe COVID-19. The results of the study were published in the journal Frontiers in Immunology. T-cell immunity is one of the key mechanisms used by the human body to fight virus infections. The staging ground for cell immunity development is the presentation of virus peptides […]

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SARS-CoV-2 DNA vaccine tested in animal model

Vaccines against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are being rolled out worldwide to control the COVID-19 (coronavirus disease 2019) pandemic. Multiple vaccines are necessitated to address the variant epidemics and also overcome the challenges that may be posed by the current vaccines (such as high cost, or low immunogenicity). In this context, a team of experts has […]

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CAR-T Cell Toxicity and Safety Profiles

Chimeric antigen receptor T cells are genetically modified to target specific cells; they have been used in research-based cancer treatments. Treatment is associated with numerous side effects and research is being performed on how to reduce them. Skip to What are Chimeric antigen receptor T cells? Clinical uses for chimeric antigen receptor T cells Chimeric antigen receptor T cells toxicity […]

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What is Cutaneous T-Cell Lymphoma?

Cutaneous T-cell lymphomas are a group of T-cell related cancers that mainly affect the skin. There are many different treatment options available for Cutaneous T-cell lymphomas with varying degrees of success. Skip to Cutaneous T-cell lymphoma Pathogenesis and pathophysiology of cutaneous T-cell lymphoma Screening and diagnosis for cutaneous T-cell lymphoma Treatments for cutaneous T-cell lymphoma Cutaneous T-cell lymphoma. Image Credit: […]

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T-cell test EIGHT TIMES better at detecting past coronavirus infection

New T-cell test is EIGHT TIMES better at detecting whether a patient had COVID than antibody tests, study claims The new test looks for T-cells, a type of white blood cells that  binds to and kills viruses, to determine if someone was infected with coronavirus in the past In a pre-print study, researchers tested at samples from 2,200 people in […]

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