Seniors have the potential to transform economy and the healthcare system

The 2020s are seeing a silver surge as populations around the world continue to age. While Japan has the highest percentage of senior citizens in the world, other countries in Europe and North America are quickly catching up. However, an ageing society could mean new potential for health and the economy, according panelist at the ‘Silver Health & Economy: New Demographics, New […]

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RNA quality control system goes awry in frontotemporal lobar degeneration

Researchers at Osaka University have identified a fault in the RNA quality control system of cells that leads to the haywire production of toxic proteins in frontotemporal lobar degeneration and amyotrophic lateral sclerosis (FTLD/ALS). Their new study, published in the EMBO Journal, shows that an abnormality of the C9orf72 gene produces toxic proteins that hinder the cells’ ability to destroy […]

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Study provides insights into how Zika virus suppresses the host immune system

A research team led by scientists at the University of California, Riverside, has outlined how the Zika virus, which constituted an epidemic threat in 2016, suppresses the immune system of its host. The Zika virus, or ZIKV, spreads through mosquito bites and sexual intercourse. Currently, no approved vaccine or antivirals against ZIKV exist. “Suppressing host immunity is a common strategy […]

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Immune system could be trained to spot drug-resistant cancers

Aggressive cancers could be treated with immunotherapies that direct the immune system to kill cancer cells with specific drug resistance-causing mutations, a major new study suggests. Drug resistance mutations which restore activity of the BRCA1 or BRCA2 genes as a way of avoiding the effects of drug treatment could leave tumors vulnerable to the effects of immunotherapy, the research found. […]

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The microbiome controls immune system fitness

Working alongside colleagues in Mainz, Bern, Hannover and Bonn, researchers from Charité – Universitätsmedizin Berlin, the Berlin Institute of Health (BIH) and the German Rheumatism Research Center Berlin (DRFZ) were able to show how the microbiome helps to render the immune system capable of responding to pathogens. If microbiome-derived signals are absent, relevant mediators are not released, resulting in a […]

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Researchers propose new disease classification system for obesity

Researchers are proposing a new scientifically correct and medically actionable disease classification system for obesity, according to a paper published online in Obesity, the flagship journal of The Obesity Society. The proposed disease classification system is based on the concept Adiposity-Based Chronic Disease (ABCD). The diagnostic term reflects both the pathophysiology and clinical impact of obesity as a chronic disease. […]

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Researcher’s technology differentiates between Parkinson’s disease and multiple system atrophy

Scientists have found a way to distinguish between two progressive neurodegenerative diseases, Parkinson’s disease (PD) and multiple system atrophy (MSA), using a technology developed by a researcher at The University of Texas Health Science Center at Houston (UTHealth). The discovery was published today in Nature. It is challenging to distinguish between the two diseases because the early signs are similar—disturbances […]

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