Dementia study reveals how proteins interact to stop brain signals

Fresh insights into damaging proteins that build up in the brains of people with Alzheimer’s disease could aid the quest for treatments. A study in mice reveals how the two proteins work together to disrupt communication between brain cells. Scientists observed how proteins—called amyloid beta and tau—team up to hamper key genes responsible for brain messaging. By changing how genes […]

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Rotavirus cell invasion triggers a cacophony of calcium signals

To successfully set off disease, rotavirus, a virus that causes severe diarrhea and vomiting in children around the world, must invade cells of the gastrointestinal track and trigger a surge of calcium inside the cells. How this surge occurs has not been clarified, but a report in the journal Scientific Reports released today shows in cinematic detail the dynamic changes […]

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Targeting chemical signals between the gut and brain could lead to new treatment for obesity

New research published in The Journal of Physiology has shed light on how to disrupt chemical signals that affect how much someone eats, which could lead to a method for helping manage obesity. Obesity is one of today’s most prevalent public health concerns. In the UK it affects around 1 in every 4 adults and around 1 in every 5 […]

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