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(HealthDay)—During a period of delta variant predominance, there was no increase in the proportion of patients who were admitted to an intensive care unit (ICU), received invasive mechanical ventilation (IMV), or died while hospitalized, according to research published in the Oct. 22 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report. Christopher A. […]
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A large international study in hospitalized patients with severe COVID-19 has shown that while a higher dose of steroids did not significantly reduce mortality, there was a trend towards benefit without increased side effects. Published today in the Journal of the American Medical Association, the study compared the standard 6mg dose of the steroid dexamethasone with 12mg in patients requiring […]
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During the entire pandemic, physicians treating patients with severe COVID-19 pneumonia have continuously looked for hints and signs on what may enable patients to have better outcomes. A team of physicians at the Renaissance School of Medicine at Stony Brook University has discovered that for patients with severe COVID-19 pneumonia who had higher ferritin in their blood upon admission and […]
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In a study published online February 25, 2021 in The New England Journal of Medicine, a repurposed drug used to treat arthritis did not significantly improve the outcomes of patients with severe COVID-19 pneumonia. Results of the Phase III clinical trial, conducted by an international team led by senior author Atul Malhotra, MD, research chief of pulmonary, critical care and […]
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Until now, the reason why the drug levodopa (L-Dopa), which reduces the motor symptoms of Parkinson’s disease, declines in efficacy after a few years’ use has been unknown. A side effect that then often occur is involuntary movements. A Swedish–French collaboration, led from Uppsala University, has now been able to connect the problems with defective metabolism of L-Dopa in the […]
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Rotavirus is a major cause of diarrhea and vomiting, especially in children, that results in approximately 128,000 deaths annually. The virus triggers the disease by infecting enterocyte cells in the small intestine, but only a fraction of the susceptible cells has the virus. In the mid-90s, scientists proposed that the small portion of infected cells promotes severe disease by sending […]
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The risk of serious adverse effects on the blood status and bone marrow of patients during chemotherapy can be predicted by a model developed at Linköping University, Sweden. This research may make it possible to use genetic analysis to identify patients with a high probability of side effects. The study has been published in npj Systems Biology and Applications. It […]
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TUESDAY, Oct. 27, 2020 — When adults with Down syndrome contract COVID-19, their risk of dying is much higher than the norm, a large, new study finds. The researchers found that of over 8 million British adults, those with Down syndrome were four times more likely to be hospitalized with COVID-19, and 10 times more likely to die due to […]
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Around the world, immunologists who retooled their labs to join the fight against SARS-CoV-2 are furiously trying to explain why some people get so sick while others recover unscathed. The pace is dizzying, but some clear trends have emerged. One area of focus has been the production of antibodies—powerful proteins capable of disabling and killing invading pathogens like viruses. Of […]
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Warning: Graphic images With bonfire night just around the corner and large events cancelled, one mum is warning people not to try to light fires at home after a horrific accident left her scarred for life. Zoe Ciereszko, 37, from Halifax, West Yorkshire, constructed a DIY bonfire in her back garden in September. But when it wouldn’t light, she used petrol, […]
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