How rotavirus causes severe gastrointestinal disease

Rotavirus is a major cause of diarrhea and vomiting, especially in children, that results in approximately 128,000 deaths annually. The virus triggers the disease by infecting enterocyte cells in the small intestine, but only a fraction of the susceptible cells has the virus. In the mid-90s, scientists proposed that the small portion of infected cells promotes severe disease by sending […]

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Predicting the risk of severe side effects of cancer treatment

The risk of serious adverse effects on the blood status and bone marrow of patients during chemotherapy can be predicted by a model developed at Linköping University, Sweden. This research may make it possible to use genetic analysis to identify patients with a high probability of side effects. The study has been published in npj Systems Biology and Applications. It […]

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People With Down Syndrome Face Higher Risk of Severe COVID-19

TUESDAY, Oct. 27, 2020 — When adults with Down syndrome contract COVID-19, their risk of dying is much higher than the norm, a large, new study finds. The researchers found that of over 8 million British adults, those with Down syndrome were four times more likely to be hospitalized with COVID-19, and 10 times more likely to die due to […]

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COVID-19 causes some patients’ immune systems to attack their own bodies, which may contribute to severe illness

Around the world, immunologists who retooled their labs to join the fight against SARS-CoV-2 are furiously trying to explain why some people get so sick while others recover unscathed. The pace is dizzying, but some clear trends have emerged. One area of focus has been the production of antibodies—powerful proteins capable of disabling and killing invading pathogens like viruses. Of […]

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Mum's dress catches fire and causes severe burns thanks to garden bonfire

Warning: Graphic images With bonfire night just around the corner and large events cancelled, one mum is warning people not to try to light fires at home after a horrific accident left her scarred for life. Zoe Ciereszko, 37, from Halifax, West Yorkshire, constructed a DIY bonfire in her back garden in September. But when it wouldn’t light, she used petrol, […]

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Urban air pollution may make COVID-19 more severe for some

As the pandemic persists, COVID-19 has claimed more than 200,000 lives in the United States and damaged the public health system and economy. In a study published on September 21 in the journal The Innovation, researchers at Emory University found that long-term exposure to urban air pollution may have made COVID-19 more deadly. “Both long-term and short-term exposure to air […]

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Difficulty breathing and COPD key predictors for severe COVID-19

Shortness of breath (dyspnoea) is the only symptom of COVID-19 significantly associated with severe cases of the disease and admission to intensive care units (ICU), according to a new systematic review and meta-analysis led by UCL. The findings, published in MedRxiv as a pre-print prior to peer-review, also showed that underlying health conditions do not all present the same risk […]

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Sleeping pills reduce suicidal thoughts in patients with severe insomnia

Insomnia is a driver of suicide, and particularly people with severe insomnia may safely benefit from taking a sedative to help address their sleep problems as it reduces their suicidal thoughts, investigators report. “If you have a patient who complains that their sleep has taken a turn for the worse then there is reason to open the door to a […]

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More severe OSA leads to higher blood pressure in patients with resistant hypertension

In patients with high blood pressure resistant to treatment who also have obstructive sleep apnea (OSA), the more severe their OSA, the higher their blood pressure, according to new research published online in the Annals of the American Thoracic Society. In “Prevalence, Characteristics and Association of Obstructive Sleep Apnea with Blood Pressure Control in Patients with Resistant Hypertension,” Esther Sapiña-Beltrán […]

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Mum says son's severe eczema was cleared by £7.99 'miracle' cream

‘Having your first baby can be a stressful time as it is, but every day was so difficult as he was so upset and in pain and discomfort,’ said Pui. ‘He wasn’t able to learn as quickly or meet physical milestones like other babies. ‘It felt so cruel to hold his arms down physically as he was using his natural […]

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