Severe Acute Respiratory Syndrome Archives

Curcumin nanosystems could be powerful COVID-19 therapeutics

04/16/2021

With new variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerging, the coronavirus disease 2019 (COVID-19) pandemic is far from over. While the global vaccine rollout has moved at an impressive speed, the search for new safe, effective, and targeted therapies is still on. Now, a new study in Biomedicine and Pharmacotherapy reviews the potential for curcumin, a natural […]

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Long-COVID-19 is a significant risk in recovered patients post-hospitalization

04/03/2021

The ongoing coronavirus disease 2019 (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pathogen, has claimed the lives of over 2.79 million people worldwide. However, the long-term effects of the virus on human health and lifespan are less well known. A new study, which appeared in the British Medical Journal, reports on a retrospective study to […]

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Rare genetic variant may explain severe COVID-19 in young healthy male patients

04/01/2021

The novel coronavirus disease 2019 (COVID-19) pandemic has now been spreading for over a year, but several mysteries surrounding its diverse outcomes remain. How is it that some young healthy individuals contract the infection(caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and become critically unwell? Why do others, who are older and have underlying comorbidities, have less severe […]

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Nanoparticles elicit neutralizing antibodies to diverse SARS-CoV-2 variants

03/31/2021

Spike-protein-based nanoparticle vaccine candidates were retained longer in follicular dendritic cells and showed higher germinal center reactions in lymph node follicles compared to soluble spike protein vaccine. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected hundreds of millions worldwide since its emergence more than a year ago. The virus has also been mutating throughout the pandemic, with several […]

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Antibody agents effective at neutralizing European, South African, and United States SARS-CoV-2 variants

03/29/2021

Researchers in the United States have demonstrated the effectiveness of three antibody agents at neutralizing recently emerged variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent responsible for the coronavirus disease 2019 (COVID-19) pandemic. The team showed that one full-length antibody and two antibody domains each effectively neutralized pseudotyped virus containing key mutations found within the B.1.1.7 […]

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New covalent and non-covalent SARS-CoV-2 inhibitors discovered in silico

03/28/2021

With the onset of the coronavirus disease 2019 (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), it came to light that there were no specific and highly effective preventive or therapeutic agents against this virus. The result has been an enormous amount of studies reporting the efficacy or otherwise of novel drug candidates or repurposed drugs […]

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Delaying second dose of Pfizer-BioNTech SARS-CoV-2 vaccine may be feasible in some cases

03/12/2021

Researchers in Spain have conducted the most extensive study to date investigating the effectiveness of vaccinating healthcare workers with a single dose of the Pfizer-BioNTech vaccine to protect against coronavirus disease 2019 (COVID-19). The team says one dose of the vaccine induced a much stronger antibody response against the causative agent – severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – […]

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Research demonstrates multivalent nanobodies overcome SARS-CoV-2 variant mutations

03/10/2021

Since the start of the COVID-19 (coronavirus disease 2019) pandemic in late December 2019, the etiological agent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) of this disease has caused more than 2.6 million deaths worldwide from over 117 million reported infections. However, as new vaccines are administered against the ancestral strain, many mutated variants of the virus are emerging across […]

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How do viruses evolve in bats?

03/09/2021

Bats have played a crucial epidemiological role in the evolution of many viruses and house many coronaviruses. Until 2002, coronaviruses had been known to cause mild respiratory ailments in human beings. However, this notion changed in the same year when a bat-borne virus caused the severe acute respiratory syndrome (SARS) pandemic. Review: Coronaviruses in humans and animals: the role of […]

Health News Coronavirus Disease COVID-19, evolution, Genes, genome, Immune System, pandemic, protein, Public Health, research, respiratory, SARS, Severe Acute Respiratory, Severe Acute Respiratory Syndrome, syndrome, virus

Small negative lifestyle changes during COVID-19 lockdown could accumulate, say researchers

03/08/2021

An interesting new study by researchers in Australia, which has been published in the journal PLOS ONE, suggests that lifestyle changes due to pandemic restrictions on outdoor mobility have been small. But they warn that these may accumulate over time. The coronavirus disease 2019 (COVID-19) pandemic, caused by the rapid and extensive spread of the severe acute respiratory syndrome coronavirus […]

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