Scientists discover immune cell behavior that plays a key role in Alzheimer’s disease

A new study has pinpointed a small group of cells in the brain which could be crucial to understanding how Alzheimer’s disease begins and how to slow its progression. This discovery could help research into treatment for the disease by focusing on this key group of cells in the brain. Alzheimer’s disease is the most common type of dementia, affecting […]

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Scientists reveal how brain cells in Alzheimer’s go awry, lose their identity

Despite the prevalence of Alzheimer’s, there are still no treatments, in part because it has been challenging to study how the disease develops. Now, scientists at the Salk Institute have uncovered new insights into what goes awry during Alzheimer’s by growing neurons that resemble—more accurately than ever before—brain cells in older patients. And like patients themselves, the afflicted neurons appear […]

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Scientists develop diagnostic test that can detect the virus that causes COVID-19 even when it mutates

A team of scientists led by Nanyang Technological University, Singapore (NTU Singapore) has developed a diagnostic test that can detect the virus that causes COVID-19 even after it has gone through mutations. Called the VaNGuard (Variant Nucleotide Guard) test, it makes use of a gene-editing tool known as CRISPR, which is used widely in scientific research to alter DNA sequences […]

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Scientists identify genetic pathway that suppresses Lou Gehrig’s Disease

Professor Chunghun Lim and his research team in the Department of Biological Sciences unveiled a neuroprotective pathway that suppresses Lou Gehrig’s Disease (ALS). Nucleocytoplasmic transport (NCT) defects have been implicated in neurodegenerative diseases, such as C9ORF72-associated amyotrophic lateral sclerosis and frontotemporal dementia (C9-ALS/FTD). In this study, the research team has identified a neuroprotective pathway of like-Sm protein 12 (LSM12) and […]

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Scientists develop blood test to predict environmental harms to children

Scientists at Columbia University Mailman School of Public Health developed a method using a DNA biomarker to easily screen pregnant women for harmful prenatal environmental contaminants like air pollution linked to childhood illness and developmental disorders. This approach has the potential to prevent childhood developmental disorders and chronic illness through the early identification of children at risk. While environmental factors—including […]

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Scientists discover how COVID-19 virus causes multiple organ failure in mice

UCLA researchers are the first to create a version of COVID-19 in mice that shows how the disease damages organs other than the lungs. Using their model, the scientists discovered that the SARS-CoV-2 virus can shut down energy production in cells of the heart, kidneys, spleen and other organs. “This mouse model is a really powerful tool for studying SARS-CoV-2 […]

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The surprising way scientists can trace COVID-19 outbreaks

The idea of testing sewage might sound as gross as it gets, but what if we told you that that our waste could hold the key for figuring out where coronavirus clusters are brewing?  Some scientists say it could be useful to consider testing sewage to predict where a COVID-19 cluster might appear next, because sewage can show where the […]

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Scientists to Infect Volunteers With COVID-19 in Challenge Trial

TUESDAY, Oct. 20, 2020 — British scientists are infecting healthy volunteers with COVID-19, in hopes of speeding up vaccine development, TheWashington Postreported Tuesday. Led by scientists at Imperial College London, people in this challenge trial will be guaranteed treatment if they become ill. The United States says human challenge trials might be too risky or unnecessary. But for the British, […]

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Scientists show jet lag conditions impair immune response in mice

Imagine you’ve just arrived in Paris. Your body thinks it should be midnight—a restorative time when your cells typically proofread DNA, organize and store energy, and perform other essential chores—but, instead, the sun is up and you’re awake. On a molecular level, your cells are stressed, trying to catch up to new environmental conditions. Shiftwork and experimental models of frequent […]

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