Mapping an effective immune response to COVID-19

Melbourne researchers have systematically mapped the immune response to COVID-19 identifying how antibodies develop in response to SARS-CoV2 and new insights into why some people develop severe disease. The team, led by University of Melbourne Professor Katherine Kedzierska, a laboratory head at the Peter Doherty Institute for Infection and Immunity (Doherty Institute), identified that multiple arms of the immune system […]

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Scientists show jet lag conditions impair immune response in mice

Imagine you’ve just arrived in Paris. Your body thinks it should be midnight—a restorative time when your cells typically proofread DNA, organize and store energy, and perform other essential chores—but, instead, the sun is up and you’re awake. On a molecular level, your cells are stressed, trying to catch up to new environmental conditions. Shiftwork and experimental models of frequent […]

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‘Deep dive’ into biology of kidney tumors identifies markers of response to immunotherapy

Treatments for kidney cancer have improved considerably over the past few decades. In 1988, when Memorial Sloan Kettering oncologist Robert Motzer started researching the disease, the average survival was less than one year. There were no approved therapies at the time besides surgery. By 2005, with the development of targeted drugs such as sunitinib (Sutent), survival nearly tripled. Today, with […]

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This is how we can improve response to the next pandemic

To Richard M. Carpiano, a pandemic is just as much of a social science issue as it is a medical one. A professor of public policy and sociology at the University of California, Riverside, Carpiano specializes in public health and medical sociology, analyzing how various social factors impact population health around the world. Carpiano began studying trends in vaccine uptake […]

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Strong public health response in China slowed coronavirus transmission, study finds

Swift isolation and quarantine policies as well as city lockdowns imposed by the Chinese government in late January 2020 significantly decreased the transmission rate of COVID-19, new research led by the Yale School of Public Health finds. Apart from these nationwide policies, public health measures implemented by provincial and local authorities since late January, such as mask wearing, social distancing, […]

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Novel targeted drug induced positive response for VHL-associated kidney cancer

In an international trial led by researchers at The University of Texas MD Anderson Cancer Center, treatment with MK-6482, the small molecule inhibitor of hypoxia-inducible factor (HIF)-2a was well tolerated and resulted in clinical responses for patients with von Hippel-Lindau disease (VHL)-associated renal cell carcinoma (RCC). The results of the Phase II trial were shared today in an oral presentation […]

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Study reveals missing link in mechanisms underlying fight-or-flight response

We’ve all felt the effects of an adrenaline rush. Faced with danger, real or perceived, the heart beats faster, breathing quickens and muscles tighten as the body prepares to fight a threat or flee from it. The role of adrenaline in triggering the fight-or-flight response is one of the most well-studied phenomena in biology. However, the precise molecular mechanisms for […]

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Céline Dion Is Being Body-Shamed Again for Being Too Thin—But Her Response Is Perfect

Like a lot of celebrities, Céline Dion has long had to contend with body critics. But now that comments calling her out for being extremely thin  are circulating once again, she's decided to respond to the gossip and point-blank explain why she maintains such a slender shape. "I do ballet. I do a lot of stretching and I work out because it […]

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Dietary factors affecting gut microbiome may influence response to immunotherapy in melanoma patients

Among melanoma patients treated with anti-PD-1 immunotherapy, consumption of a high-fiber diet was associated with higher gut microbiome diversity and better response to treatment, according to data presented during a media preview of the AACR Annual Meeting 2019, to be held March 29-April 3 in Atlanta. “We found that diet and supplements appear to have an effect on a patient’s […]

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Meghan Markle's Response to Being Called a "Fat Lady" Was Perfect

Royal pregnancies are subject to endless scrutiny and there are bound to be at least one or two, uh, awkward moments. The key is to take it all in stride, and that’s exactly how Meghan Markle responded to being called a “fat lady” during a visit to an animal shelter on Wednesday. The Duchess of Sussex, who happens to be […]

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