Researchers find promising new treatment approach for multiple sclerosis

In an animal model of multiple sclerosis (MS), decreasing the amount of a protein made in the liver significantly protected against development of the disease’s characteristic symptoms and promoted recovery in symptomatic animals, UTSW scientists report. The findings, published online today by Science Translational Medicine, could lead to a new treatment strategy for this neurological disease and other conditions marked […]

Read more

Researchers map structural variants in 17,795 sequenced human genomes

A large team of researchers affiliated with a very large number of medical institutions across the U.S. and also three from Finland, two from Mexico, and one from the U.K. has mapped structural variants in 17,795 sequenced genomes. In their paper published in the journal Nature, the group describes their work, which was meant to explore structural variants in genome […]

Read more

Researchers uncover cellular mechanism involved in Krabbe disease

A group of researchers at the University at Buffalo have published a paper that clarifies certain cellular mechanisms that could lead to improved outcomes in patients with globoid cell leukodystrophy, commonly known as Krabbe disease. The paper, titled “Macrophages Expressing GALC Improve Peripheral Krabbe Disease by a Mechanism Independent of Cross-Correction,” was published today (May 5) in the journal Neuron. […]

Read more

Researchers find eating with someone else makes people eat smaller portions, but more often

A team of researchers at the University of Tokyo has found that people tend to consume smaller amounts of food when they are with someone else than when alone, but eat more often. In their paper published in the journal Royal Society Open Science, the group describes experiments they carried out with volunteer eaters and what they found. Prior studies […]

Read more

Researchers develop novel approach to capture hard-to-view portion of colon in 3D

In a groundbreaking discovery, researchers at Children’s Hospital of Philadelphia (CHOP) developed a new imaging method that allows scientists to view the enteric nervous system (ENS) – a key part of the human colon—in three dimensions by making other colon cells that normally block it invisible. The ENS has previously only been visible in thin tissue slices that provide limited […]

Read more

Researchers propose new disease classification system for obesity

Researchers are proposing a new scientifically correct and medically actionable disease classification system for obesity, according to a paper published online in Obesity, the flagship journal of The Obesity Society. The proposed disease classification system is based on the concept Adiposity-Based Chronic Disease (ABCD). The diagnostic term reflects both the pathophysiology and clinical impact of obesity as a chronic disease. […]

Read more

Researchers discover receptor chain involved in atopic dermatitis

Atopic dermatitis, a chronic inflammatory disorder, affects some 30 million Americans every year. It is the most common cause of eczema, a condition marked by unbearably itchy, flaky patches of skin. A new Tel Aviv University study identifies the precise receptor chain involved in the development of atopic dermatitis. The researchers hope to develop an antibody based on this research […]

Read more

Researcher’s technology differentiates between Parkinson’s disease and multiple system atrophy

Scientists have found a way to distinguish between two progressive neurodegenerative diseases, Parkinson’s disease (PD) and multiple system atrophy (MSA), using a technology developed by a researcher at The University of Texas Health Science Center at Houston (UTHealth). The discovery was published today in Nature. It is challenging to distinguish between the two diseases because the early signs are similar—disturbances […]

Read more

Researchers uncover the genomics of health

Most diseases have a genetic component. To better understand disease, researchers led by the Garvan Institute of Medical Research are analysing genetic information to determine what keeps us healthy. In a world first, the team has compiled a genome reference database of thousands of healthy older Australians, which has the potential to predict disease-linked gene variants more accurately than has […]

Read more
1 2 3 6