Researchers create human airway stem cells from patients’ cells

For the first time, researchers have successfully created airway basal stem cells in vitro from induced pluripotent stem cells by reprogramming blood cells taken from patients. Given that airway basal cells are defined as stem cells of the airways because they can regenerate the airway epithelium in response to injury, this study may help accelerate research on diseases impacting the […]

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Researchers identify the mechanism behind bone marrow failure in Fanconi anaemia

Fanconi anemia (FA) is a genetic disease affecting small children characterized by bone-marrow failure, developmental abnormalities and predisposition to multiple forms of cancer. The molecular mechanisms behind FA are inherited mutations in genes encoding for DNA repair proteins, leading to irreversible bone marrow failure. The exact mechanisms how these genetic mutations lead to the exhaustion of stem cells from the […]

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U.S., French Researchers Awarded Nobel Prize in Chemistry

WEDNESDAY, Oct. 7, 2020 — American and French scientists have won the 2020 Nobel Prize in chemistry for their work developing the revolutionary gene-editing tool CRISPR-Cas9. The award for University of California at Berkeley biochemist Jennifer Doudna and Emmanuelle Charpentier of France was announced Wednesday, The Washington Post reported. “This year’s prize is about rewriting the code of life,” said […]

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Researchers probe how aggression leads to more aggression

Like a champion fighter gaining confidence after each win, a male mouse that prevails in several successive aggressive encounters against other male mice will become even more aggressive in future encounters, attacking faster and for longer and ignoring submission signals from his opponent. This phenomenon is interesting to people who study the neuroscience of behavior, because aggression is an innate, […]

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Researchers advance COVID-19 antibody knowledge

Researchers at the University of Tennessee Health Science Center working with colleagues at MD Anderson Cancer Center in Houston have found that some antibodies to SARS-CoV-2, the virus that causes COVID-19, are more protective than others, when it comes to reinfection. This information, discovered from the joint study and published online in the Journal of Clinical Investigation’s JCI Insight, has […]

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Researchers seek rapid way to produce proteins necessary to assess potential vaccine components

Dr. Gerd Mittelstädt from Te Herenga Waka-Victoria University of Wellington’s Ferrier Research Institute is contributing to the search for a COVID-19 vaccine by finding a rapid way to produce the proteins needed to assess potential vaccine components. Working alongside other University researchers and the Malaghan Institute for Medical Research, as part of Vaccine Alliance Aotearoa New Zealand-Ohu Kaupare Huaketo, Dr. […]

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Researchers discover new pathway in TDP-43 related dementias

Recent work published by researchers at the University of Kentucky’s Sanders-Brown Center on Aging (SBCoA) highlights what the lead investigator calls the ‘cornerstone’ of her lab. Maj-Linda Selenica, assistant professor at SBCoA, led the study recently published in BBA Molecular Basis of Disease. She says their approach was unconventional as it looked at the molecular mechanisms implicated in TDP-43 biology, […]

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Researchers now better understand ovarian cancer tumors and treatment outcomes

After nearly four years of work, a group of researchers and clinicians from the University of Colorado (CU) published a paper this week in the Clinical Cancer Research that shares findings from research looking at how the composition of ovarian cancer tumors changes during chemotherapy and contributes to therapeutic response. While the standard of care consisting of surgery and chemotherapy […]

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Researchers visualize the retina’s function at the cellular level

While there is no cure for blindness and macular degeneration, scientists have accelerated the process to find a cure by visualizing the inner workings of the eye and its diseases at the cellular level. In an effort led by UW Medicine, researchers successfully modified the standard process of optical coherence tomography (OCT) to detect minute changes in response to light […]

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Researchers expect viral transmission of COVID-19 may increase as temperatures drop

Last winter, infectious disease specialists hoped the transmission rates of SARS-CoV-2—the virus behind COVID-19—would rapidly decline like the seasonal flu with the coming of warmer months. Unfortunately, this big drop didn’t materialize, or so we thought. Preliminary results from research at Johns Hopkins Medicine suggest that a large component of the pandemic’s initial spread was indeed dependent on temperature. In […]

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