Researchers start to uncover the pandemic’s impact on mental health

Depression remained common during the pandemic and worsened for some people, according to a new study aiming to cast light on links between the pandemic and mental health. Researchers examined the records of 4,633 people at a large health care system in Utah who were screened for depression during a primary care visit. They completed a questionnaire before the pandemic […]

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Researchers investigate role of gene associated with Alzheimer’s disease in brain’s immune cells

When immune cells move throughout the brain, they act as the first line of defense against viruses, toxic materials and damaged neurons, rushing over to clear out them. Researchers at Indiana University School of Medicine have been investigating how these immune cells in the brain—microglia—relate to a gene mutation recently found in Alzheimer’s disease patients. They published their findings today […]

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Researchers outline the connection between inflammation and depression

In a paper published recently in Pharmacological Reviews, Emory University School of Medicine researchers outlined the impact of inflammation on motivation as it relates to depression. The researchers propose that low grade inflammation affects brain chemicals and brain circuits that regulate motivation, ultimately leading to motivational deficits and a loss of interest or willingness to engage in usually pleasurable activities […]

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Researchers find a higher than expected risk of myocarditis in young men after full vaccination.

Males between 16 and 29 years of age have an increased risk of developing heart problems after receiving a second dose of coronavirus vaccines made by Pfizer-BioNtech or Moderna, according to a large new analysis published on Wednesday in the New England Journal of Medicine. The study, conducted in Israel, estimated that nearly 11 of every 100,000 males in that […]

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Researchers link PTSD, anxiety fears in women with history of military sexual trauma

A new Veterans Affairs study finds a strong link between PTSD symptom severity and anxiety sensitivity among female Veterans who have experienced military sexual trauma. The researchers say treating the anxiety problem may be a way to ease core PTSD symptoms. Anxiety sensitivity reflects a fear of physical sensations that accompany anxiety. A person with high levels of anxiety sensitivity […]

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Researchers pinpoint how PARP inhibitors combat BRCA1 and BRCA2 tumor cells

A team of Massachusetts General Hospital (MGH) researchers has discovered how an important class of anti-cancer drugs called PARP inhibitors works, a finding that could help improve treatment and prolong survival for patients with breast cancer and other malignancies. PARP (poly[ADP-ribose] polymerase) inhibitors such as olaparib (Lynparza), rucaparib (Rubraca) and niraparib (Zejula) are used to treat patients with cancers of […]

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Researchers propose strategies to speed global vaccine availability

In a new paper published in the journal Vaccine: X, public health experts from Columbia University Mailman School of Public Health, the University of Oslo, and Spark Street Advisors highlight actions to accelerate access to vaccines globally. The paper reviews the vaccine research and development process and proposes areas where reforms could increase access, speed time to market and decrease […]

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Researchers uncover mechanism related to severe post-COVID-19 disease in children

A multidisciplinary team from MassGeneral Hospital for Children (MGHfC), Brigham and Women’s Hospital and other institutions have identified the mechanism of how an extremely rare but serious post-COVID-19 complication develops in children and adolescents. Led by MGHfC pediatric pulmonologist Lael Yonker, MD, researchers determined that viral particles remaining in the gut long after an initial COVID-19 infection can travel into […]

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Researchers identify novel approach to repair the human heart

A team of scientists from Loyola University Chicago’s Stritch School of Medicine have discovered a critical component for renewing the heart’s molecular motor, which breaks down in heart failure. Approximately 6.2 million Americans have heart failure, an often fatal condition characterized by the heart’s inability to pump enough blood and oxygen throughout the body. This discovery could represent a novel […]

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Researchers report COVID-19 found in penile tissue could contribute to ED

University of Miami Miller School of Medicine researchers are the first to demonstrate that COVID-19 can be present in the penis tissue long after men recover from the virus. The widespread blood vessel dysfunction, or endothelial dysfunction, that results from the COVID-19 infection could then contribute to erectile dysfunction, or ED, according to the study recently published in the World […]

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