Sensing infection, suppressing regeneration

In a new peer-reviewed publication, University of Illinois at Chicago researchers describe how the body’s response to inflammation, which helps to fight many kinds of infections, also can counterproductively suppress much-needed cell repair and regeneration in blood vessels. In the study, which is published in Immunity, the researchers describe an enzyme that blocks the ability of blood vessel cells to […]

Read more

Imaging nerve regeneration provides insight to success of repair

When peripheral nerves are injured and surgically repaired, regeneration must occur in a timely fashion to restore sensory and motor function. Current methods for following nerve regeneration provide only limited information and may delay a needed second surgical intervention and lead to poor outcomes. Richard Dortch, Ph.D., (Radiology and Radiological Sciences), Wes Thayer, MD, Ph.D., (Plastic Surgery), and colleagues evaluated […]

Read more

Researcher reports skin properties that may limit cancer and aid stem cell regeneration

Two images published in a Cell Stem Cell paper in September 2018 summarize years of relentless questioning on how skin stem cells regenerate, which has driven much of the research of Valentina Greco, Ph.D., Carolyn Walch Slayman Professor of Genetics and professor of cell biology and of dermatology, and her lab members. The side-by-side images feature individual mouse cells in […]

Read more