receptor Archives - eHealth Week

Curcumin nanosystems could be powerful COVID-19 therapeutics

04/16/2021

With new variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerging, the coronavirus disease 2019 (COVID-19) pandemic is far from over. While the global vaccine rollout has moved at an impressive speed, the search for new safe, effective, and targeted therapies is still on. Now, a new study in Biomedicine and Pharmacotherapy reviews the potential for curcumin, a natural […]

Health News ACE2, Biomedicine, cell, compound, coronavirus, Coronavirus Disease COVID-19, Curcumin, drugs, Efficacy, Enzyme, in vivo, molecule, Nanoparticle, nanoparticles, Nanostructures, pandemic, pathogen, protein, quercetin, receptor, respiratory, SARS, SARS-CoV-2, Severe Acute Respiratory, Severe Acute Respiratory Syndrome, Spike Protein, syndrome, therapeutics, turmeric, vaccine, virus

A collaborative effort to evaluate treatment of liver and pancreatic tumors

04/08/2021

HOUSTON, DENVER and CHICAGO ? The University of Texas MD Anderson Cancer Center and TriSalus Life Sciences today announced a strategic research collaboration to evaluate the treatment of tumors of the pancreas and liver by integrating interventional delivery of SD-101, an investigational toll-like receptor 9 (TLR9) agonist, in combination with checkpoint inhibition immunotherapy. Under the agreement, MD Anderson and TriSalus […]

Health News Adenocarcinoma, cancer, Drug Delivery, immunotherapy, liver, melanoma, Oncology, pancreas, receptor, research, therapeutics, Vasculature

Study offers localized treatment direction for a cause of Crohn's disease

04/08/2021

People with Crohn's disease are typically treated with powerful anti-inflammatory medications that act throughout their body, not just in their digestive tract, creating the potential for unintended, and often serious, side effects. New research from the lab of Mark Sundrud, PhD, at Scripps Research, Florida suggests a more targeted treatment approach is possible. Crohn's disease develops from chronic inflammation in […]

Health News Anti-Inflammatory, bile:, blood, cancer, chronic, Crohn's Disease, gene, inflammation, liver, receptor, research, Small Intestine

Research provides insights on why redheads exhibit altered sensitivity to pain

04/03/2021

New research led by investigators at Massachusetts General Hospital (MGH) provides insights on why people with red hair exhibit altered sensitivity to certain kinds of pain. The findings are published in Science Advances. In people with red hair (as in numerous other species of animals with red fur), the pigment-producing cells of the skin–called melanocytes–contain a variant form of the […]

Health News cancer, cell, hair, hospital, Melanin, melanoma, Pain, receptor, research, Skin

Rare genetic variant may explain severe COVID-19 in young healthy male patients

04/01/2021

The novel coronavirus disease 2019 (COVID-19) pandemic has now been spreading for over a year, but several mysteries surrounding its diverse outcomes remain. How is it that some young healthy individuals contract the infection(caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and become critically unwell? Why do others, who are older and have underlying comorbidities, have less severe […]

Health News blood, cell, Chromosome, coronavirus, Coronavirus Disease COVID-19, diabetes, gene, Genes, genetic, genome, inflammation, Intensive Care, Nucleotide, obesity, oxygen, pandemic, pneumonia, receptor, respiratory, SARS, SARS-CoV-2, Severe Acute Respiratory, Severe Acute Respiratory Syndrome, syndrome, virus, X chromosome

Antibody agents effective at neutralizing European, South African, and United States SARS-CoV-2 variants

03/29/2021

Researchers in the United States have demonstrated the effectiveness of three antibody agents at neutralizing recently emerged variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent responsible for the coronavirus disease 2019 (COVID-19) pandemic. The team showed that one full-length antibody and two antibody domains each effectively neutralized pseudotyped virus containing key mutations found within the B.1.1.7 […]

Health News ACE2, antibodies, Antibody, assay, cell, coronavirus, Coronavirus Disease COVID-19, Medical School, Mutation, pandemic, protein, receptor, research, respiratory, SARS, SARS-CoV-2, Severe Acute Respiratory, Severe Acute Respiratory Syndrome, Spike Protein, syndrome, therapeutics, virus

New covalent and non-covalent SARS-CoV-2 inhibitors discovered in silico

03/28/2021

With the onset of the coronavirus disease 2019 (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), it came to light that there were no specific and highly effective preventive or therapeutic agents against this virus. The result has been an enormous amount of studies reporting the efficacy or otherwise of novel drug candidates or repurposed drugs […]

Health News ACE2, Angiotensin, Angiotensin-Converting Enzyme 2, cell, coronavirus, Coronavirus Disease COVID-19, drugs, E.coli, Efficacy, Enzyme, influenza, Knockout, Ligand, molecule, pandemic, protein, receptor, respiratory, SARS, SARS-CoV-2, Serine, Severe Acute Respiratory, Severe Acute Respiratory Syndrome, Spike Protein, syndrome, therapeutics, virus

IONTAS identifies novel SARS-CoV-2 neutralising antibodies

03/23/2021

IONTAS Limited (IONTAS) and FairJourney Biologics S.A (FJB)., leaders in the discovery and optimization of fully human antibodies, have announced the identification of neutralizing antibodies, which bind to multiple emerging SARS-CoV-2 variants. The results, generated from a combination of phage display technology and B-cell receptor repertoire sequencing of hospitalized COVID-19 patients, have identified potent neutralizing antibodies with distinct mechanisms of […]

Health News antibodies, Antibody, cell, Clinical trial, protein, receptor, SARS, SARS-CoV-2, Spike Protein, virus

Research demonstrates multivalent nanobodies overcome SARS-CoV-2 variant mutations

03/10/2021

Since the start of the COVID-19 (coronavirus disease 2019) pandemic in late December 2019, the etiological agent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) of this disease has caused more than 2.6 million deaths worldwide from over 117 million reported infections. However, as new vaccines are administered against the ancestral strain, many mutated variants of the virus are emerging across […]

Health News ACE2, Angiotensin, Angiotensin-Converting Enzyme 2, antibodies, Antibody, antigen, Cas9, coronavirus, Coronavirus Disease COVID-19, CRISPR, Cytometry, Enzyme, flow cytometry, Genes, Glycoprotein, Locus, Nanobodies, pandemic, protein, Pseudovirus, receptor, research, respiratory, SARS, SARS-CoV-2, Severe Acute Respiratory, Severe Acute Respiratory Syndrome, syndrome, virus

UK and South African SARS-CoV-2 variants show higher binding affinity to host cell receptor

02/24/2021

Public health officials are concerned over new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants emerging in various parts of the world. The B.1.1.7 variant was first found in the United Kingdom and found to have the N501Y mutation that allows it to have a faster transmission rate than previous strains. The B.1.351 variant was detected in South Africa and […]

Health News ACE2, binding affinity, cell, coronavirus, Coronavirus Disease COVID-19, genetic, Immune System, Mutation, Public Health, receptor, research, respiratory, SARS, SARS-CoV-2, Severe Acute Respiratory, Severe Acute Respiratory Syndrome, syndrome

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