Screening mammography could benefit men at high risk of breast cancer

Selective mammography screening can provide potentially lifesaving early detection of breast cancer in men who are at high risk for the disease, according to a landmark study published in the journal Radiology. Breast cancer in men is a rare but often deadly disease. The American Cancer Society projects that 2,670 new cases of invasive breast cancer will be diagnosed in […]

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Novel anti-cancer nanomedicine for efficient chemotherapy

Researchers at the University of Helsinki in collaboration with researchers from Åbo Akademi University,Finland and Huazhong University of Science and Technology,China have developed a new anti-cancer nanomedicine for targeted cancer chemotherapy. This new nano-tool provides a new approach to use cell-based nanomedicines for effcient cancer chemotherapy. Exosomes contain various molecular constituents of their cell of origin, including proteins and RNA. […]

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Patients taking nivolumab experience five-fold increase in overall survival compared to chemotherapy: Five-year outcomes from the randomized, phase 3 trials checkmate 017/057: nivolumab vs. docetaxel in previously treated NSCLC

Pooled data on two clinical trials demonstrate patients taking nivolumab realized a greater than five-fold increase in five-year overall survival rate compared with the chemotherapy docetaxel. The presentation was made today by Dr. Scott Gettinger of Yale Comprehensive Cancer Center, New Haven, Conn., at the IASLC 2019 World Conference on Lung Cancer, hosted by the International Association for the Study […]

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Gold nanoparticles shown to be safe and effective treatment for prostate cancer

Biocompatible gold nanoparticles designed to convert near-infrared light to heat have been shown to safely and effectively ablate low- to intermediate-grade tumors within the prostate, according to a study conducted at the Icahn School of Medicine and published in the journal Proceedings of the National Academy of Sciences. This treatment could offer patients a targeted therapy option that would preserve […]

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A simpler way to choose the sex of offspring by separating X and Y sperm: Differential gene activity by the two sex chromosomes allows X-bearing sperm to be slowed down

A simple, reversible chemical treatment can segregate X-bearing sperm from Y-bearing sperm, allowing dramatic alteration of the normal 50/50 male/female offspring ratio, according to a new study by Masayuki Shimada and colleagues at Hiroshima University, published on August 13 in the open-access journal PLOS Biology. The study was performed in mice, but the technique is likely to be widely applicable […]

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Human cells assembling into fractal-like clusters

Tree-like branching structures are everywhere in the human body, from the bronchial system in the lungs to the spidering capillaries that supply blood to the extremities. Researchers have long worked to understand the cellular signaling needed to build these intricate structures, but new research suggests that simple physics may play an underappreciated role. The research, published in the Proceedings of […]

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Better tools, better cancer immunotherapy

In the journal Science Immunology, researchers from DTU Health Technology and Jacobs University in Bremen have just published their cutting-edge research demonstrating advancement in detection of a certain type of immune cells, called T cells. Improved detection of T cells have several therapeutic implications. For example, in cancer immunotherapy (a therapeutic approach that engage patients own immune cells) characterization of […]

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Study links progenitor cells to age-related prostate growth: As the organ enlarges, the risk for cancer and other diseases increases

The prostates of older mice contain more luminal progenitor cells — cells capable of generating new prostate tissue — than the prostates of younger mice, UCLA researchers have discovered. The observation, published in Cell Reports, helps explain why, as people age, the prostate tends to grow, leading to an increased risk for prostate cancer and other conditions. “Understanding what’s causing […]

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Researchers unlock cancer cells’ feeding mechanism, central to tumor growth: The findings could lead to new treatments by blocking tumor growth at its roots

An international team led by researchers from the University of Cincinnati and Japan’s Keio and Hiroshima universities has discovered the energy production mechanism of cancerous cells that drives the growth of the nucleolus and causes tumors to rapidly multiply. The findings, published Aug. 1 in the journal Nature Cell Biology, could lead to the development of new cancer treatments that […]

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