Researchers pinpoint hierarchy of breast cancer cells as potential cause for treatment resistance

You might have heard the old proverb, “It takes a village to raise a child.” University of Cincinnati instructor Syn Yeo, Ph.D., thinks the same analogy applies when it comes to cells and the growth of cancer, particularly breast cancer. In his recent study, published in the journal eLife, Yeo, research instructor in the department of cancer biology at the […]

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CAR T cell therapy: Potential for considerable savings

Chimeric antigen receptor (CAR) T cell therapy is a new and in some cases highly effective form of immunotherapy to treat certain types of cancer of the blood and lymph system. This promising treatment comes at a cost, however: The manufacturers charge up to EUR 320,000 for the production of immune cells for a single patient. By determining the fixed […]

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Study illustrates huge potential of human, artificial intelligence collaboration in medicine

Artificial Intelligence (AI) is increasingly being used in medicine to support human expertise. However, the potential of these applications and the risks inherent in the interaction between human and artificial intelligence have not yet been thoroughly researched. The fear is often expressed that in future, as soon as AI is of sufficient quality, human expertise will become dispensable and therefore […]

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World must prepare for ‘potential pandemic’: WHO chief

The World Health Organization chief on Monday warned countries to prepare for a “potential pandemic” of new coronavirus, calling the sudden increase in cases in Iran, Italy and South Korea “deeply concerning”. Tedros Adhanom Ghebreyesus also said, however, that a WHO joint mission to China that concluded on Monday found that the virus there “peaked” between January 23 and February […]

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New study identifies potential path forward for brachial plexus injury recovery

On average, an estimated three out of every 1,000 newborns will suffer a brachial plexus injury during birth, damaging the bundle of nerves that connect the brain and spinal cord to the shoulders, arms and hands. In the most traumatic cases, even with surgery and physical therapy as an infant, there is no treatment that can guarantee a full recovery. […]

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Reducing aluminium intake can minimize potential health risks

In addition, the contributions of the various sources of total aluminum intake by the population were compared with one another. A high intake of aluminum compounds can cause, among other things, neurotoxic developmental disorders as well as damage the kidneys, liver and bones. The BfR bases its assessment of the population’s aluminum intake from food on the latest consumption and […]

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Mini-kidneys grown from stem cells provide new insights into kidney disease and potential therapies

An international team of researchers led by Nanyang Technological University, Singapore (NTU Singapore) has grown ‘miniature kidneys’ in the laboratory that could be used to better understand how kidney diseases develop in individual patients. The mini kidneys, known as kidney organoids, were grown outside the body from skin cells derived from a single patient who has polycystic kidney disease, one […]

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Laboratory studies identify a potential way to treat human cancers with ARID1A mutations

A new study shows that tumor cells depleted of ARID1A—a protein that acts as a cancer suppressor—become highly sensitive to anticancer poly ADP ribose polymerase (PARP) inhibitor drugs after radiation treatment. The research, led by Johns Hopkins Kimmel Cancer Center researchers, could advance efforts to treat many human cancers with loss of ARID1A that are resistant to current standard treatments, […]

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Analyzing colon cancer proteins and genes uncovers new potential treatments

Analyzing both the entire set of genes and all the proteins produced by colon cancer tissues from patient samples has revealed a more comprehensive view of the tumor that points at novel cancer biological mechanisms and possible new therapeutic strategies. This multidisciplinary and multi-institutional study led by researchers at Baylor College of Medicine and published in the journal Cell, strongly […]

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Study finds test of protein levels in the eye a potential predictor of (future) Alzheimer’s disease

Low levels of amyloid-β and tau proteins, biomarkers of Alzheimer’s disease (AD), in eye fluid were significantly associated with low cognitive scores, according to a new study published in the Journal of Alzheimer’s Disease. Led by researchers at Boston Medical Center, the study is the first to connect these known AD protein biomarkers in the eye to mental status. These […]

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