No evidence blanket ‘do-not-resuscitate’ orders for COVID-19 patients are necessary

It’s inappropriate to consider blanket do-not-resuscitate orders for COVID-19 patients because adequate data is not yet available on U.S. survival rates for in-hospital resuscitation of COVID-19 patients and data from China may not relate to U.S. patients, according to a new article published today in Circulation: Cardiovascular Quality and Outcomes, an American Heart Association journal. There is a presumption that COVID-19 […]

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Genome-wide pattern found in tumors from brain cancer patients predicts life expectancy

For the past 70 years, the best indicator of life expectancy for a patient with glioblastoma (GBM)—the most common and the most aggressive brain cancer—has simply been age at diagnosis. Now, an international team of scientists has experimentally validated a predictor that is not only more accurate but also more clinically relevant: a pattern of co-occurring changes in DNA abundance […]

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Patients improve after heart cell therapy

Four of six critically ill COVID-19 (coronavirus) patients significantly improved after receiving an experimental therapeutic designed to reduce inflammation, a major cause of death from this disease, according to a case series published by Cedars-Sinai and Capricor Therapeutics. The four patients got well enough to be discharged from the hospital. The therapeutic, known as CAP-1002, contains cardiosphere-derived cells (CDCs) that […]

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New antigen test for detecting COVID-19 could help triage patients during the pandemic

One of the most important tools in stopping the spread of the novel coronavirus, SARS-CoV-2, is rapid, reliable and relatively cheap diagnostic testing at the point of care. Scientists in Europe recently evaluated the frontline capabilities of a commercially available, 15-minute disposable antigen test to detect COVID-19 infections. Their findings, reported in Frontiers in Medicine, suggest the test could be […]

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EULAR: Hydroxychloroquine use in lupus patients ‘does not seem to prevent COVID-19’

The current outbreak of COVID-19 represents a source of concern for the management of systemic lupus erythematous, SLE, patients. These patients have an increased risk of severe infections due to their underlying disease, the use of immunosuppressive drugs, as well as the potential presence of organ damage associated with their disease. Hydroxychloroquine, HCQ, a drug that is currently part of […]

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Mysterious blood clots in COVID-19 patients have doctors alarmed

As doctors learn more about what makes COVID-19 so severe for some patients, they have discovered a mysterious and potentially lethal complication of the disease: blood clots. Many doctors have reported seeing an alarming number of COVID-19 patients with blood clots — gel-like clumps in the blood that can cause serious problems, such as heart attack and stroke, according to […]

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All ethical principles are violated: palliative physician, complains about wrong handling with Corona patients

Again and again it is in the Corona-crisis, the question is, how many intensive care beds are available for the treatment of Covid-19-patients. A palliative care practitioner laments the, in his view, entirely the wrong approach. You should provide patients with pre-existing conditions in old age, faced with the choice of whether you want to take the rigors of such […]

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Botanical drug is shown to help patients with head and neck cancers

In a UCLA-led phase I clinical trial, a new plant-based drug called APG-157 showed signs of helping patients fight oral and oropharyngeal cancers. These cancers are located in the head and the neck. APG-157 is made up of multiple compounds produced by plants, including curcumin. UCLA Jonsson Comprehensive Cancer Center researchers found that treatment with this botanical drug resulted in […]

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Disability, quality of life, mood may affect sleep in IBD patients

(HealthDay)—Sleep quality is associated with mood state, disability, and quality of life among patients with inflammatory bowel disease (IBD), according to a study published online Jan. 16 in Scientific Reports. Carla Marinelli, from the University Hospital of Padua in Italy, and colleagues evaluated sleep quality among 166 IBD patients to identify possible independent risk factors for sleep disturbance, including demographic […]

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Study examines genetic testing in diverse young breast cancer patients over a decade

Breast cancer patients diagnosed under age 50 represent 18 percent of new invasive breast cancer cases in the United States. Compared to postmenopausal women, younger women are more likely to develop aggressive subtypes of breast cancer, have a worse prognosis with increased risk of recurrence, and have higher overall mortality. Young breast cancer patients also are more likely to be […]

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