India virus patients suffocate from low oxygen amid surge

Authorities scrambled anew Saturday to supply medical oxygen to Indian hospitals where COVID-19 patients were suffocating amid low supplies as the country with the world’s worst coronavirus surge set a new global daily record of infections for the third straight day. The 346,786 infections over the past day brought India’s total past 16 million, behind only the United States. The […]

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Microglia, Stockholm syndrome and miraculous cures in glioblastoma patients

Despite access to some of the best possible medical care in the world, Senators John McCain and Edward Kennedy both died within 18 months of their diagnosis of glioblastoma, an aggressive form of brain cancer. While this deadly outcome typifies the nature of this disease, some glioblastoma patients see exceptional benefits from chemotherapy and survive beyond expectations. Why this happens […]

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Study reveals cancer immunotherapy patients at most risk of life-threatening side effects

Many patients with cancer receive immune checkpoint inhibitors that strengthen their immune response against tumor cells. While the medications can be life-saving, they can also cause potentially life-threatening side effects in internal organs. This double-edged sword makes it challenging for clinicians to decide who should be considered candidates for treatment. A new analysis led by researchers at Massachusetts General Hospital […]

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SARS-CoV-2 positivity in asymptomatic-screened dental patients

Asymptomatic carriage of SARS-CoV-2 is a potentially significant source of transmission, yet remains relatively poorly understood. The study “SARS-CoV-2 Positivity in Asymptomatic-screened Dental Patients” published in the Journal of Dental Research (JDR), investigated SARS-CoV-2 infection in asymptomatic dental patients to inform community surveillance and improve understanding of risks in the dental setting. Thirty-one dental care centers across Scotland invited asymptomatic […]

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Helping childhood-onset lupus patients stay healthy as adults

UT Southwestern researchers have identified factors that put patients with childhood-onset lupus at elevated risk for poor outcomes, such as end-stage renal disease or death, as they transition from pediatric to adult health care. The findings, published online in Seminars in Arthritis and Rheumatism, emphasize the precarious nature of this period and shine a spotlight on areas prime for intervention […]

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Forty-three percent of melanoma patients have chronic complications from immunotherapies

Chronic side effects among melanoma survivors after treatment with anti-PD-1 immunotherapies are more common than previously recognized, according to a study published March 25 in JAMA Oncology. The chronic complications, which occurred in 43% of patients, affected the joints and endocrine system most commonly, and less often involved salivary glands, eyes, peripheral nerves and other organs. These complications may be […]

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‘I’ve aged 30 years’: long COVID patients battle acute symptoms

Difficulty breathing, concentrating and even walking: five months after being diagnosed with COVID-19, Violaine Cousineau continues to suffer severe symptoms that prevent her from resuming normal life. “I feel like I’ve aged 30 years in a few months,” the 47-year-old Canadian tells AFP. Sitting in her kitchen and wearing a mask, Cousineau gestures with her hands as she speaks, as […]

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First lab-grown mini-thyroids use patients’ own tissue

Hormones produced by the thyroid gland are essential regulators of organ function. The absence of these hormones either through thyroid dysfunction due to, for example, irradiation, thyroid cancer or autoimmune disease or thyroidectomy leads to symptoms like fatigue, feeling cold, constipation, and weight gain. Hypothyroidism is estimated to affect up to 11% of the global population. Although hypothyroidism can be […]

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Medical bill worries tied to worse outcomes for cancer patients

(HealthDay)—Financial worries can hamper the success of cancer treatment and raise patients’ risk of death, according to a new study that offers the first evidence of such a link. “The association we found was very strong, and very concerning,” said senior study author Dr. Anurag Singh, director of radiation research at Roswell Park Comprehensive Cancer Center in Buffalo, N.Y. “If […]

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Study finds short window for donating convalescent plasma to COVID-19 patients

The optimal timeframe for donating convalescent plasma for use in COVID-19 immunotherapy, which was given emergency use authorization by the Food and Drug Administration in August 2020, is within 60 days of the onset of symptoms, according to a new Penn State-led study. The research also reveals that the ideal convalescent plasma donor is a recovered COVID-19 patient who is […]

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