Cell-free DNA detects pathogens and quantifies damage

A common problem in diagnosing infectious disease is that the presence of a potential pathogen in the body does not necessarily mean the patient is sick. This can be particularly challenging for the treatment of organ transplant recipients, who often grapple with infection as well as complications related to immunosuppression. A new Cornell study, “A Cell-Free DNA Metagenomic Sequencing Assay […]

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How pathogens are controlled when tissue is deprived of adequate oxygen supply

Infected tissue has a low concentration of oxygen. The body’s standard immune mechanisms, which rely on oxygen, can then only function to a limited extent. How does the immune system nevertheless manage to control bacteria under such conditions? The working groups led by PD Dr. Anja Lührmann and Prof. Dr. Jonathan Jantsch have investigated this question in collaboration with other […]

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