Mechanisms help pancreatic cancer cells avert starvation

A new study reveals the mechanism that helps pancreatic cancer cells avoid starvation within dense tumors by hijacking a process that pulls nutrients in from their surroundings. Led by researchers at NYU Grossman School of Medicine, the study explains how changes in the gene RAS—known to encourage the abnormal growth seen in 90 percent of pancreatic cancer patients—also accelerate a […]

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One-two punch drug combination offers hope for pancreatic cancer therapy

Scientists at Sanford Burnham Prebys Medical Discovery Institute have identified a combination of two anti-cancer compounds that shrank pancreatic tumors in mice—supporting the immediate evaluation of the drugs in a clinical trial. U.S. Food and Drug Administration (FDA)-approved versions of the compounds are used today to treat certain leukemias and solid tumors, including melanoma. The study was published in Nature […]

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Pancreatic and bowel cancer soars by 10% across the world since 1990

Cases of pancreatic and bowel cancer have soared by 10% across the world since 1990, finds review of 195 countries as scientists blame obesity Experts say spiralling obesity and type 2 diabetes rates fuelling rise in cancers  Were 1.8million new cases of bowel cancer in 2017, up by 9.5 per cent since 1990 Pancreatic cancer struck 195,000 people in 1990, […]

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UK urine test that can detect early-stage pancreatic cancer starts clinical study

A urine test that can detect early stage pancreatic cancer has reached the final stage of validation before being developed for use with patients. If successful, this non-invasive urine test would be the first in the world to help clinicians detect the highly lethal cancer at an early stage—enabling many more people to have surgery to remove their tumor, which […]

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Stage 4 pancreatic cancer: Symptoms, treatment, and survival rates

According to research from 2015, about 53 percent of people with pancreatic cancer receive a diagnosis when the cancer is in stage 4. Treatment aims to prolong life and manage pain and other symptoms. In this article, we describe the symptoms of pancreatic cancer and outline the treatment options when the cancer is in stage 4. What is stage 4 […]

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