Discovery of unknown brain-repair process could lead to new epilepsy treatments

University of Virginia School of Medicine researchers have discovered a previously unknown repair process in the brain that they hope could be harnessed and enhanced to treat seizure-related brain injuries. Common seizure-preventing drugs do not work for approximately a third of epilepsy patients, so new and better treatments for such brain injuries are much needed. UVA’s discovery identifies a potential […]

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Review of Australian COVID-19 research finds lack of collaboration, crucial gaps

A study looking at the landscape of COVID-19 research in Australia shows an impressive rapid response in clinical trials to the pandemic, but researchers say the haste in funding, development and implementation highlight new challenges. In a study published in the Medical Journal of Australia, University of Sydney researchers looked at clinical trials conducted in Australia focused on the COVID-19 […]

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80 percent of asthma-related hospitalizations are avoidable

One in ten school-aged children in Australia have a current diagnosis of asthma. Every year, there are around 40,000 asthma hospitalisations and over 40 per cent of these are in children aged younger than 14 years old. Approximately 80 per cent of these asthma-related hospital presentations are potentially avoidable through a standardized comprehensive care pathway for children with asthma. These […]

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FDA adds warning of rare reaction risk to Johnson & Johnson COVID vaccine

WASHINGTON — U.S. regulators on Monday added a new warning to Johnson & Johnson’s COVID-19 vaccine about links to a rare and potentially dangerous neurological reaction, but said it’s not entirely clear the shot caused the problem. The Food and Drug Administration announced the new warning, flagging reports of Guillain-Barre syndrome, an immune system disorder that can causes muscle weakness […]

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The ethics of split liver transplantation: Analyzing case studies to make the right decision

Split liver transplantation (SLT) provides an opportunity to divide a donor liver and offer transplants to two small patients, one or both of whom could be a child. SLT, which is underused in the United States, could be used more widely to decrease the number of deaths of people on transplant waiting lists. In a new article, researchers address some […]

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Novel study of high-potency cannabis shows some memory effects

Even before the pandemic made Zoom ubiquitous, Washington State University researchers were using the video conferencing app to research a type of cannabis that is understudied: the kind people actually use. For the study, published in Scientific Reports, researchers observed cannabis users over Zoom as they smoked high-potency cannabis flower or vaped concentrates they purchased themselves from cannabis dispensaries in […]

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Faulty memories of our past whereabouts: The fallacy of an airtight alibi

When someone is suspected of criminal activity, one of the most important questions they are asked is if they have a credible alibi. Playing back past events in our minds, however, is not like playing back a video recording. Recollections of locations, dates, and companions can become muddled with the passage of time. If a suspect’s memories are out of […]

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Study reveals mechanisms of increased infectivity and antibody resistance of SARS-CoV-2 variants

Combining structural biology and computation, a Duke-led team of researchers has identified how multiple mutations on the SARS-CoV-2 spike protein independently create variants that are more transmissible and potentially resistant to antibodies. By acquiring mutations on the spike protein, one such variant gained the ability to leap from humans to minks and back to humans. Other variants—including Alpha, which first […]

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Pediatricians ID cause of muscle breakdown in rare disease found on newborn screening

It was a nagging mystery: A rare-disease expert at UPMC Children’s Hospital of Pittsburgh had found a successful treatment for two of the deadliest symptoms of one of the more common classes of rare diseases diagnosed by newborn screenings, but one symptom—painful episodes of muscle breakdown that land victims in intensive care—persisted. Today, the scientists announce in the journal Clinical […]

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