Novel targeted drug induced positive response for VHL-associated kidney cancer

In an international trial led by researchers at The University of Texas MD Anderson Cancer Center, treatment with MK-6482, the small molecule inhibitor of hypoxia-inducible factor (HIF)-2a was well tolerated and resulted in clinical responses for patients with von Hippel-Lindau disease (VHL)-associated renal cell carcinoma (RCC). The results of the Phase II trial were shared today in an oral presentation […]

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Researchers develop novel approach to capture hard-to-view portion of colon in 3D

In a groundbreaking discovery, researchers at Children’s Hospital of Philadelphia (CHOP) developed a new imaging method that allows scientists to view the enteric nervous system (ENS) – a key part of the human colon—in three dimensions by making other colon cells that normally block it invisible. The ENS has previously only been visible in thin tissue slices that provide limited […]

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Lebanon announces first novel coronavirus case

Credit: CC0 Public Domain The first case of the novel coronavirus in Lebanon was confirmed on Friday, the health minister said, adding that two other suspected cases were being investigated. “We confirmed the first case today,” Hamad Hassan said at a press conference in Beirut. The COVID-19 virus was found in a 45-year-old Lebanese woman who had travelled from Qom […]

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Researchers develop novel heart pump to help people with heart failure

Dr. David Adlam, associate professor and interventional cardiologist in the Department of Cardiovascular Sciences and Piyal Samara-Ratna, Mechanical Engineer in the Space Research Centre, have joined forces to combine medical and space research to develop a pump to help people with heart failure. The new left ventricular assist device (LVAD) is an artificial heart pump used as an interim support […]

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Pediatric hematologists introduce a novel way to treat pediatric hemophilia A patients

An innovative way to treat pediatric hemophilia A patients using a combination approach has seen early success at the Aflac Cancer and Blood Disorders Center of Children’s Healthcare of Atlanta, with researchers from Emory University School of Medicine. Now known as the Atlanta Protocol, in a nod to where the approach was developed, the new method involves treating patients with […]

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Novel model for studying intestinal parasite could advance vaccine development

The intestinal parasite Cryptosporidium, which causes a diarrheal disease, is very good at infecting humans. It’s the leading cause of waterborne disease from recreational waters in the United States. Globally, it’s a serious illness that can stunt the growth of, or even kill, infants and young children. And people with compromised immune systems, such as those with HIV/AIDS, are also […]

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Scientists identify a novel neural circuit mediating visually evoked innate defensive responses

Fear overgeneralization, a condition that limits the ability to discriminate between safety and threat, is an important pathological characteristic of anxiety-related syndromes such as post-traumatic stress disorder (PTSD), generalized anxiety disorder (GAD) and panic disorder. However, unlike traditional conditioned fear, the mechanism of processing innate fear is largely unknown. Prof. Wang Liping and his colleagues Zhou Zheng and Liu Xuemei […]

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Novel app uses AI to guide, support cancer patients

Artificial Intelligence is helping to guide and support some 50 breast cancer patients in rural Georgia through a novel mobile application that gives them personalized recommendations on everything from side effects to insurance. The app, called MyPath, adapts to each stage in a patient’s cancer journey. So the information available on the app—which runs on a tablet computer—regularly changes based […]

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Novel technique accurately assesses cardiovascular risks

A new noninvasive technique for imaging the carotid artery offers advantages over other imaging methods and could provide an earlier, more accurate assessment of cardiovascular disease risk, according to a study published in the journal Radiology. The carotid arteries are the blood vessels located on the left and right side of the neck that bring oxygenated blood to the head. […]

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