Body’s natural signal carriers can help melanoma spread

A new study from Finland sheds fresh light on how melanoma cells interact with other cells via extracellular vesicles they secrete. The researchers found that extracellular vesicles secreted by melanoma cells use the so-called hedgehog signaling pathway to intensify the malignant properties of the cells they are targeting. The discovery can help in the development of better treatment and diagnostics […]

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Vinnie Jones health: Footballer and wife both battled same disease – what’s the symptoms?

Vinnie Jones, 54, became a household name as a professional football player before turning his talents to acting. Vinnie played 184 games in the Premier League, scoring 13 goals in the competition. Since his retirement from football, Vinnie has capitalised on his tough guy image and has appeared in a string of blockbuster films including Lock, Stock and Two Smoking […]

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Study finds genetic testing motivates behavior changes in families at risk for melanoma

Skin cancer is the most commonly diagnosed cancer in the United States, and melanoma is the most severe type of skin cancer. The National Cancer Institute estimates more than 96,000 new cases will be diagnosed this year, and the disease will cause more than 7,000 deaths. Utah has a particularly high melanoma rate. A new study led by researchers at […]

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Study may explain why immunotherapy not effective for some patients with metastatic melanoma and kidney cancer

White blood cells known as B cells have been shown to be effective for predicting which cancer patients will respond to immune checkpoint blockade (ICB) therapy, according to a study at The University of Texas MD Anderson Cancer Center. Study results will be presented April 2 at the AACR Annual Meeting 2019 in Atlanta. The study, led by Jennifer Wargo, […]

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Dietary factors affecting gut microbiome may influence response to immunotherapy in melanoma patients

Among melanoma patients treated with anti-PD-1 immunotherapy, consumption of a high-fiber diet was associated with higher gut microbiome diversity and better response to treatment, according to data presented during a media preview of the AACR Annual Meeting 2019, to be held March 29-April 3 in Atlanta. “We found that diet and supplements appear to have an effect on a patient’s […]

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Study shows immunotherapy drug helps patients with metastatic melanoma

When melanoma turns metastatic, it spreads to the brain in more than 40% of patients. A study by Yale Cancer Center researchers published today in the Journal of Clinical Oncology (JCO) shows a checkpoint inhibitor immunotherapy drug has meaningful benefit for these patients. The study is one of the first clinical trials aimed at treating the brain metastases with this […]

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