The key to making it as a health startup: strategize

The past year and a half has been a hotbed for healthcare innovation. Seeing the recent success of many digital health startups, other entrepreneurs are attempting to break into the market for themselves. But in a highly regulated and competitive industry like healthcare, finding your way in the marketplace can be a daunting challenge. “Starting a company can be complex […]

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Chemical modification of RNA could play key role in polycystic kidney disease

A chemical modification of RNA that can be influenced by diet appears to play a key role in polycystic kidney disease, an inherited disorder that is the fourth leading cause of kidney failure in the U.S., UT Southwestern researchers report in a new study. The findings, published online today in Cell Metabolism, suggest new ways to treat this incurable condition. […]

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SARS-CoV-2 hijacks two key metabolic pathways to rapidly replicate in host cells

When SARS-CoV-2, the virus that causes COVID-19, infects a human cell, it quickly begins to replicate by seizing the cell’s existing metabolic machinery. The infected cells churn out thousands of viral genomes and proteins while halting the production of their own resources. Researchers from Brigham and Women’s Hospital, Massachusetts General Hospital (MGH), and the Broad Institute, studying cultured cells shortly […]

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Cytoglobin: Key player in preventing liver disease

Researchers have discovered that the use of Cytoglobin (CYGB) as an intravenous drug could delay liver fibrosis progression in mice. CYGB, discovered in 2001 by Professor Norifumi Kawada, is present in hepatic stellate cells, the cells that produce fibrotic molecules such as collagens when the liver has acute or chronic inflammation induced by different etiologies. The enhancement of CYGB on […]

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Social connection, social support and physical exercise key to overcoming adversity

David Creswell and his daughter recently bought ice skates, and on a good week, they hit the ice every couple of days. The new winter tradition is more than just fun, said Creswell, professor of psychology and neuroscience at Carnegie Mellon University’s Dietrich College of Humanities and Social Sciences. The activity combines exercise and social interaction—two evidence-based strategies that can […]

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Blood pressure drug may be key to increasing lifespan, new study shows

Since time immemorial, people have been fascinated by ways to stop aging. Nearly every culture has stories to tell about people who lived for thousands of years, showing that extending lifespan has always been a deep desire across humanity. While modern medicine does not strive to find the fountain of youth, keen interest in promoting longevity has prompted research into […]

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Antibody Tests Are Still A Long Way From Holding The Key To Ending COVID-19

Novel coronavirus antibody tests can help determine whether a person has contracted COVID-19. COVID-19 antibodies are also being studied to determine if they could hold the key to potential treatments or vaccines. Right now, reliable COVID-19 antibody tests are not widely available, though many are currently in development. Back in mid-March, the coronavirus got me—in a subtle sneak attack. My […]

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Difficulty breathing and COPD key predictors for severe COVID-19

Shortness of breath (dyspnoea) is the only symptom of COVID-19 significantly associated with severe cases of the disease and admission to intensive care units (ICU), according to a new systematic review and meta-analysis led by UCL. The findings, published in MedRxiv as a pre-print prior to peer-review, also showed that underlying health conditions do not all present the same risk […]

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How a key brain region combines visual and spatial information to navigate

When we move through the streets of our neighborhood, we often use familiar landmarks to help us navigate. And as we think to ourselves, “OK, now make a left at the coffee shop,” a part of the brain called the retrosplenial cortex (RSC) lights up. While many studies have linked this brain region with landmark-based navigation, exactly how it helps […]

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