Antibody Tests Are Still A Long Way From Holding The Key To Ending COVID-19

Novel coronavirus antibody tests can help determine whether a person has contracted COVID-19. COVID-19 antibodies are also being studied to determine if they could hold the key to potential treatments or vaccines. Right now, reliable COVID-19 antibody tests are not widely available, though many are currently in development. Back in mid-March, the coronavirus got me—in a subtle sneak attack. My […]

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Difficulty breathing and COPD key predictors for severe COVID-19

Shortness of breath (dyspnoea) is the only symptom of COVID-19 significantly associated with severe cases of the disease and admission to intensive care units (ICU), according to a new systematic review and meta-analysis led by UCL. The findings, published in MedRxiv as a pre-print prior to peer-review, also showed that underlying health conditions do not all present the same risk […]

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How a key brain region combines visual and spatial information to navigate

When we move through the streets of our neighborhood, we often use familiar landmarks to help us navigate. And as we think to ourselves, “OK, now make a left at the coffee shop,” a part of the brain called the retrosplenial cortex (RSC) lights up. While many studies have linked this brain region with landmark-based navigation, exactly how it helps […]

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Brain tumor organoids may be key to time-sensitive treatments for glioblastomas

Lab-grown brain organoids developed from a patient’s own glioblastoma, the most aggressive and common form of brain cancer, may hold the answers on how to best treat it. A new study in Cell from researchers at Penn Medicine showed how glioblastoma organoids could serve as effective models to rapidly test personalized treatment strategies. Glioblastoma multiforme (GBM) remains the most difficult […]

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Schools, parents and grandparents hold key to unlocking China’s obesity problem

Educating parents and grandparents—as well as improving physical activity and the food provided at school—could hold the key to solving China’s obesity pandemic, according to one of the largest trials of childhood obesity prevention in the world. Over 30 million Chinese children, aged between seven and 18, are overweight or obese—placing them at greater risk of an early death and […]

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First comprehensive structural data on a key flu protein—it’s central to infection

Influenza A viruses spawn epidemics, global pandemics and sweeping outbreaks that kill millions of birds, yet only now have flu scientists obtained comprehensive, high-resolution structural data on a protein that is key to the very survival of an influenza virus. The highlighted protein is RNA polymerase, which transcribes and replicates the viral genome in the nucleus of host cells. Dr. […]

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SIRT1 plays key role in chronic myeloid leukemia to aid persistence of leukemic stem cells

Patients with chronic myeloid leukemia can be treated with tyrosine kinase inhibitors. While these effective drugs lead to deep remission and prolonged survival, primitive leukemia stem cells resist elimination during the remission and persist as a major barrier to cure. As a result, the majority of patients with chronic myeloid leukemia, or CML, require indefinite inhibitor treatment to prevent disease […]

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Mutual appreciation key to saving marriage after a stroke, study shows

Laurel Sproule knew something in her 18-year marriage was changing when she came into the kitchen and found her husband Fred just standing there. He’d suffered a recent heart attack and then a stroke, but was home, and slowly responding to therapy. Getting ready to go out one day, they needed to eat lunch first, so Laurel laid out sandwich […]

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Computer hardware originally designed for 3-D games could hold the key to replicating the human brain

Researchers at the University of Sussex have created the fastest and most energy efficient simulation of part of a rat brain using off-the-shelf computer hardware. Dr. James Knight and Prof Thomas Nowotny from the University of Sussex’s School of Engineering and Informatics have beaten a top 50 supercomputer by running brain simulations using their own GeNN software and graphics processing […]

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