Researchers discover molecule that provides dual protection against vascular inflammation

A multidisciplinary team of researchers from Duke-NUS Medical School and the Agency for Science, Technology and Research (A*STAR) in Singapore discovered a new mitochondrial peptide called MOCCI that plays an important role in regulating inflammation of blood vessel and immunity. The study, published in the journal Nature Communications, revealed how one gene encoded two molecules that provide two-pronged protection following […]

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Anti-diabetic drug metformin inhibits disease progression in Alport syndrome mouse model

Researchers from Kumamoto University (Japan) have found that the anti-diabetic drug metformin significantly prolongs the survival of mice in a model that simulates the pathology of non-diabetic chronic kidney disease (ND-CKD) by ameliorating pathological conditions like reduced kidney function, glomerular damage, inflammation and fibrosis. Metformin's mechanism is different from existing therapeutics which only treat symptoms, such as the blood pressure […]

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Study offers localized treatment direction for a cause of Crohn's disease

People with Crohn's disease are typically treated with powerful anti-inflammatory medications that act throughout their body, not just in their digestive tract, creating the potential for unintended, and often serious, side effects. New research from the lab of Mark Sundrud, PhD, at Scripps Research, Florida suggests a more targeted treatment approach is possible. Crohn's disease develops from chronic inflammation in […]

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Rare genetic variant may explain severe COVID-19 in young healthy male patients

The novel coronavirus disease 2019 (COVID-19) pandemic has now been spreading for over a year, but several mysteries surrounding its diverse outcomes remain. How is it that some young healthy individuals contract the infection(caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and become critically unwell? Why do others, who are older and have underlying comorbidities, have less severe […]

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Terry White Chemists Meloxicam

NOTICE: This Consumer Medicine Information (CMI) is intended for persons living in Australia. TERRY WHITE CHEMISTS MELOXICAM TABLETS Contains the active ingredient, meloxicam Consumer Medicine Information What is in this leaflet Read this leaflet carefully before taking your medicine This leaflet answers some common questions about meloxicam. It does not contain all the available information. It does not take the […]

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Psoriatic Arthritis Management

Psoriatic arthritis (PsA) is a chronic, autoimmune, inflammatory form of arthritis that affects 5-25% of patients afflicted by the skin condition psoriasis. In almost 60% of PsA cases, it presents in a few joints (1-4) but becomes polyarticular as the disease progresses. Polyarthritis affects both sides symmetrically and in one out of three PsA patients, it is often associated with […]

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Tevatrexed

NOTICE: This Consumer Medicine Information (CMI) is intended for persons living in Australia. TEVATREXED┬« VERSION 1.0 Pemetrexed disodium Consumer Medicine Information What is in this leaflet This leaflet answers some common questions about Pemetrexed. It does not contain all the available information. It does not take the place of talking to your doctor or pharmacist. The information in this leaflet […]

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Flucon

NOTICE: This Consumer Medicine Information (CMI) is intended for persons living in Australia. FLUCON EYE DROPS 0.1% Fluorometholone acetate Consumer Medicine Information What is in this leaflet Please read this leaflet carefully before you use any FLUCON Eye Drops. This leaflet answers some common questions about FLUCON Eye Drops. It does not contain all of the available information. It does […]

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Crystal Structure of the Human Cannabinoid Receptor CB2

Skip to: Making Crystals of the Antagonist The Structure Interaction of the Antagonist with CB2 Activation of CB2 Phytocannabinoids in the form of Cannabis plant is widely consumed by humans. Two of the cannabinoid receptors, CB1 and CB2 are the key targets of this endocannabinoid system. While CB1 is widely present across the body, CB2 is mainly present in the […]

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