New research identifies cancer types with little survival improvements in adolescents and young adults

Survival rates for adolescents and young adults diagnosed with cancer have varied considerably depending on cancer type. A new study indicates that survival for multiple cancer types in such patients has improved in recent years, but some patients diagnosed with common cancer types still show limited survival improvements. The results are published by Wiley early online in Cancer, a peer-reviewed […]

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Novel imaging agent identifies biomarker for iron-targeted cancer therapies

A new radiotracer that detects iron in cancer cells has proven effective, opening the door for the advancement of iron-targeted therapies for cancer patients. The radiotracer, 18F-TRX, can be used to measure iron concentration in tumors, which can help predict whether a not the cancer will respond to treatment. This research was published in the July issue of the Journal […]

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Study identifies resilience factors to mitigate burnout in college students

Mental health issues such as burnout and psychological distress are matters for concern among young adults, and are even more pertinent in today’s uncertain global climate. A recent paper by Yale-NUS College alumna Ms Joanna Chue (Class of 2019) and Assistant Professor of Social Sciences (Psychology) Cheung Hoi Shan identified five components of resilience that are applicable in Singapore’s cultural […]

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Research identifies obesity and infection link, as well as treatment found on healthy human skin

The list of diseases and conditions complicated by obesity is a long one; it includes heart disease, cancer, diabetes and impaired wound healing, as well as skin infections. It is not always clear, however, in what way this complication is caused. New research from the School of Pharmaceutical Science at Xiamen University and the Gallo Lab at UC San Diego […]

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‘Deep dive’ into biology of kidney tumors identifies markers of response to immunotherapy

Treatments for kidney cancer have improved considerably over the past few decades. In 1988, when Memorial Sloan Kettering oncologist Robert Motzer started researching the disease, the average survival was less than one year. There were no approved therapies at the time besides surgery. By 2005, with the development of targeted drugs such as sunitinib (Sutent), survival nearly tripled. Today, with […]

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New study identifies potential path forward for brachial plexus injury recovery

On average, an estimated three out of every 1,000 newborns will suffer a brachial plexus injury during birth, damaging the bundle of nerves that connect the brain and spinal cord to the shoulders, arms and hands. In the most traumatic cases, even with surgery and physical therapy as an infant, there is no treatment that can guarantee a full recovery. […]

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Study identifies role of specific gene in hardening of blood vessel walls

Arterial wall calcification is the buildup of calcium in the blood vessel walls, which can often be a predictor of serious cardiovascular events like heart attacks and strokes. Scientists have long pointed to family history as one possible cause for this hardening of the arteries, but a new study published in Nature Genetics implicates a specific gene—HDAC9—in the calcification of […]

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AI identifies risk of cholesterol-raising genetic disease, study finds

A new algorithm can determine whether a patient is likely to have a cholesterol-raising genetic disease that can cause early, and sometimes fatal, heart problems, reports a new study conducted by researchers at the Stanford University School of Medicine and their collaborators. The disease, known as familial hypercholesterolemia, is often misdiagnosed as garden-variety high cholesterol. “We think that less than […]

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