Researchers pinpoint how PARP inhibitors combat BRCA1 and BRCA2 tumor cells

A team of Massachusetts General Hospital (MGH) researchers has discovered how an important class of anti-cancer drugs called PARP inhibitors works, a finding that could help improve treatment and prolong survival for patients with breast cancer and other malignancies. PARP (poly[ADP-ribose] polymerase) inhibitors such as olaparib (Lynparza), rucaparib (Rubraca) and niraparib (Zejula) are used to treat patients with cancers of […]

Read more

How to manage pandemic stressors for children

Since the pandemic began, parents and researchers have been trying to understand how it affects children’s mental health. For 18 months, children have dealt with the disruption of their daily lives, fear of COVID-19 contagion, and sometimes death in the family. The emergence and spread of the coronavirus delta variant has renewed the uncertainty about young people’s safety as schools […]

Read more

How society’s inequalities showed up in COVID outcomes

Racial minorities comprise around a quarter of Utah’s population but represent a third of COVID-19 cases in the state. A similar story has played out across the country. Why have racial minorities been unequally affected by the COVID-19 pandemic? Researchers are still working out the answer to this question, but a new study from University of Utah researchers including Daniel […]

Read more

Deficiency in how gut microbiome-produced substances are detected in high blood pressure

A new study led by Monash University scientists has found that microbial genetic pathways are different in people suffering from hypertension. The research also found that those with hypertension also have a deficiency in a newly identified target gene that senses gut microbiota-derived metabolites that lower blood pressure. The study, led by Associate Professor Francine Marques from the Monash University […]

Read more

Study shows how U.S. immigration policy can have domestic health effects

After a controversial federal order suspending travel to the U.S. from seven Muslim-majority countries was signed in 2017, the number of visits to emergency departments by Minneapolis-St. Paul area residents from those nations increased significantly. And that development followed an already marked increase in primary care visits by members of the same population, which began in November 2016 following an […]

Read more
1 2 3 4 26