Brain cells can harbor and spread HIV virus to the body

Researchers have found that astrocytes, a type of brain cell can harbor HIV and then spread the virus to immune cells that traffic out of the brain and into other organs. HIV moved from the brain via this route even when the virus was suppressed by combination antiretroviral therapy (cART), a standard treatment for HIV. The study, conducted by researchers […]

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New discovery on the activity and function of MAIT cells during acute HIV infection

In a new study published in Nature Communications, researchers at Karolinska Institutet show that mucosa-associated invariant T cells (MAIT cells) of the human immune system respond with dynamic activity and reprogramming of gene expression during the initial phase of HIV infection. The study fills a knowledge gap, as previously, the function of MAIT cells during this particular phase was not […]

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New Yorkers are initiating treatment earlier after HIV infection, study shows

The most effective way to reduce HIV-related deaths and prevent onward transmission is to diagnose and treat all persons as soon as possible after HIV infection. According to a study published in Clinical Infectious Diseases, New Yorkers living with HIV are being treated sooner after infection. The time to treatment initiation was reduced in tandem with expanded HIV testing and […]

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Study urges life-saving drug treatment to combat Ukraine’s HIV epidemic

Credit: Michael S. Helfenbein University researchers finds that scaling up use of methadone and buprenorphine—medications for treating opioid use disorder known as opioid agonist therapies (OATs)—could greatly reduce HIV transmission rates and prevent deaths in Ukraine, where the disease is epidemic among people who inject drugs. The study was published in The Lancet. Annual new HIV infections in Ukraine—home to […]

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Rectal microbes influence effectiveness of HIV vaccine

Microbes living in the rectum could make a difference to the effectiveness of experimental HIV vaccines, according to researchers at the University of California, Davis. The work is published Dec. 11 in the journal mSphere. Evidence from human and animal studies with other vaccines suggests that Lactobacillus supplements can boost production of antibodies, while treatment with antibiotics can hamper beneficial […]

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Study: For babies born with HIV, start treatment right away

When babies are born with HIV, starting treatment within hours to days is better than waiting even the few weeks to months that’s the norm in many countries, researchers reported Wednesday. The findings, from a small but unique study in Botswana, could influence care in Africa and other regions hit hard by the virus. They also might offer a clue […]

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Uninfected individuals born to mothers living with HIV at risk of obesity and asthma

Adolescents and young adults who were born to mothers with HIV but remained uninfected themselves still face a greatly heightened risk of obesity and asthma-like symptoms, researchers from Massachusetts General Hospital (MGH) have found. In a study published in Journal of Acquired Immune Deficiency Syndromes (JAIDS), the team revealed for the first time that HIV-negative teens and young adults with […]

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Scientists discover a new strain of HIV for the first time since 2000

Scientists find new strain of HIV for the first time since 2000 – and they say the discovery is a step toward ending the pandemic by including it in testing, treatment and potential vaccines Scientists at Abbott Labs have confirmed that a strain of HIV that infected three people in the Democratic Republic of Congo is a new variety of […]

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Surprise finding about HIV reservoir could lead to better therapies

Antiretroviral therapy (ART) can suppress HIV to the point where the virus is nearly undetectable, and people on medication can live many years. But therapy cannot completely eradicate the virus; it persists in reservoirs inside immune cells, a phenomenon called “latency.” This latent reservoir forms even when a person begins therapy very early after infection, but the dynamics of the […]

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15 people get HIV while waiting to get access to preventative pill

At least 15 people in England contract HIV while waiting to get a place on a trial for a pill which prevents the AIDS-causing virus and is freely available in the rest of the UK Pre-exposure prophylaxis, known as PrEP, has been trialled in the UK since 2017 Freely available in Scotland, Wales and N. Ireland but access limited in England […]

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