RNA quality control system goes awry in frontotemporal lobar degeneration

Researchers at Osaka University have identified a fault in the RNA quality control system of cells that leads to the haywire production of toxic proteins in frontotemporal lobar degeneration and amyotrophic lateral sclerosis (FTLD/ALS). Their new study, published in the EMBO Journal, shows that an abnormality of the C9orf72 gene produces toxic proteins that hinder the cells’ ability to destroy […]

Read more

Hollywood braces for shutdown, Broadway goes dark

The entertainment industry prepared Thursday for an unprecedented shutdown to curb the spread of the coronavirus, canceling upcoming movies, suspending all Broadway performances and eliminating live audiences from television shows until it’s safe to welcome crowds back. To accommodate calls for social distancing, Hollywood moved to pause the normal hum of TV productions and the bustle of red-carpet movie premieres. […]

Read more