Function Archives | eHealth Week

MRI-identified damage tied to patient-reported RA function

02/29/2020

(HealthDay)—There is a consistent association between magnetic resonance imaging (MRI) findings of damage in the wrist and hand and self-reported loss of function in patients with established rheumatoid arthritis (RA) in sustained clinical remission, according to a study recently published in the International Journal of Rheumatic Diseases. Daniel Glinatsi, M.D., Ph.D., from the Copenhagen Center for Arthritis Research at Rigshospitalet […]

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New discovery on the activity and function of MAIT cells during acute HIV infection

01/14/2020

In a new study published in Nature Communications, researchers at Karolinska Institutet show that mucosa-associated invariant T cells (MAIT cells) of the human immune system respond with dynamic activity and reprogramming of gene expression during the initial phase of HIV infection. The study fills a knowledge gap, as previously, the function of MAIT cells during this particular phase was not […]

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Injection of virus-delivered gene silencer blocks ALS degeneration, saves motor function

12/23/2019

Writing in Nature Medicine, an international team headed by researchers at University of California San Diego School of Medicine describe a new way to effectively deliver a gene-silencing vector to adult amyotrophic lateral sclerosis (ALS) mice, resulting in long-term suppression of the degenerative motor neuron disorder if treatment vector is delivered prior to disease onset, and blockage of disease progression […]

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Autonomic nervous system appears to function well regardless of mode of childbirth

07/31/2019

Late in pregnancy, the human body carefully prepares fetuses for the rigors of life outside the protection of the womb. Levels of cortisol, a stress hormone, ramp up and spike during labor. Catecholamines, another stress hormone, also rise at birth, helping to kick start the necessary functions that the baby will need to regulate breathing, heartbeat, blood pressure and energy […]

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Energy drinks may increase risk of heart function abnormalities and blood pressure changes

05/29/2019

Drinking 32 ounces of an energy drink in a short timespan may increase blood pressure and the risk of electrical disturbances in the heart, which affect heart rhythm, according to a small study published in Journal of the American Heart Association, the Open Access Journal of the American Heart Association/American Stroke Association. The study enrolled 34 healthy volunteers between the […]

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A new genetic tool to modify and understand gene function

05/22/2019

Scientists of the National Center for Cardiovascular Research (CNIC) led by Rui Benedito have developed a new genetic tool called iSuRe-Cre that provides certainty in Cre-inducible genetic modifications, a key technique for understanding gene function. Most analysis of gene function in biomedical research relies on the use of Cre-lox technology. Since its introduction in 1994, this technology has revolutionized biomedical […]

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‘I’d go to a family function and not talk to anyone’: the social impact of hearing loss

03/02/2019

Alan Edwards can still remember the day he heard clearly for the first time. “It was an overwhelming sense of calm,” Edwards says, remembering sitting on a park bench and laughing as he enjoyed the sounds he’d never heard before. Alan Edwards found himself feeling isolated when his hearing deteriorated. “It was really fascinating and amazing.” Having struggled with genetic, […]

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Hearing Loss Linked to Subjective Cognitive Function Decline

02/01/2019

FRIDAY, Feb. 1, 2019 — For older men, hearing loss is associated with subjective cognitive function (SCF) decline, according to a study published online Jan. 29 in Alzheimer’s & Dementia. Sharon G. Curhan, M.D., from Brigham and Women’s Hospital and Harvard Medical School in Boston, and colleagues conducted a longitudinal study from 2008 to 2016 involving 10,107 men aged 62 […]

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Opioids Offer Small Improvement in Pain, Physical Function

12/19/2018

TUESDAY, Dec. 18, 2018 — Opioid use is associated with small improvements in pain and physical functioning in patients with chronic noncancer pain, according to research published in the Dec. 18 issue of the Journal of the American Medical Association. Jason W. Busse, Ph.D., from McMaster University in Hamilton, Ontario, Canada, and colleagues conducted a systematic review of randomized clinical […]

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Study shows in older people, type 2 diabetes is associated with a decline in brain function over five years

12/14/2018

New research published in Diabetologia (the journal of the European Association for the Study of Diabetes [EASD]) shows that in older people living in the community, type 2 diabetes (T2D) is associated with a decline in verbal memory and fluency over 5 years. However, contrary to previous studies, the decrease in brain volume often found in older people with T2D […]

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