Exercise in mid-life won’t improve cognitive function in women

For middle-aged women, exercise has many health benefits, but it may not help maintain cognitive function over the long term, according to a new UCLA Health study. The study observed a diverse group of roughly 1,700 women over a 21-year period starting when the women’s average age was 45. In the study, women’s cognitive ability was tested in three key […]

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Structure and Function of the Cell Nucleus

Skip to Nuclear Membrane (nuclear envelope) Nucleoskeleton Nuclear Pore (Nuclear Pore Complex) Nucleolus Chromosomes The cell nucleus is the site of many important biological functions of the eukaryotic cell. These processes include transcription, replication, splicing and ribosome biogenesis. The effect of these processes extends to affecting cellular metabolism and growth. The nucleus contains approximately 2m of DNA which is enmeshed […]

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Children exposed to tobacco smoke at home have worse heart function as adults

The more secondhand tobacco smoke children breathe at home while growing up, the higher chance they have of developing markers of decreased heart function as adults, according to preliminary research to be presented at the American Heart Association’s Scientific Sessions 2020. “We already know from previous studies that children exposed to secondhand smoke are more likely to have structural differences […]

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Nut consumption causes changes in sperm DNA function, study shows

Many environmental and lifestyle factors have been implicated in the decline of sperm quality, with diet being one of the most plausible factors identified in recent years. Moreover, several studies have reported a close association between the alteration of specific sperm DNA methylation signatures and semen quality. To date, however, no randomized clinical trials (RCT) have been published that assess […]

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Study reveals restoration of retinal and visual function following gene therapy

A breakthrough study, led by researchers from the University of California, Irvine, results in the restoration of retinal and visual functions of mice models suffering from inherited retinal disease. Published today in Nature Biomedical Engineering, the paper, titled, “Restoration of visual function in adult mice with an inherited retinal disease via adenine base editing,” illustrates the use of a new […]

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Ultraviolet B exposure expands proenkephalin+ regulatory T cells with a healing function

Ultraviolet B (UVB) is used as an effective therapy for individuals with psoriasis and atopic dermatitis because it has an immunosuppressive effect. The immune system develops to protect the body from infection or cancer. Its activation affects many physiological functions. Regulatory T (Treg) cells, expressing CD25 and Foxp3, constitute about 5-10% of peripheral CD4+T cells and work as brake on […]

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MRI-identified damage tied to patient-reported RA function

(HealthDay)—There is a consistent association between magnetic resonance imaging (MRI) findings of damage in the wrist and hand and self-reported loss of function in patients with established rheumatoid arthritis (RA) in sustained clinical remission, according to a study recently published in the International Journal of Rheumatic Diseases. Daniel Glinatsi, M.D., Ph.D., from the Copenhagen Center for Arthritis Research at Rigshospitalet […]

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New discovery on the activity and function of MAIT cells during acute HIV infection

In a new study published in Nature Communications, researchers at Karolinska Institutet show that mucosa-associated invariant T cells (MAIT cells) of the human immune system respond with dynamic activity and reprogramming of gene expression during the initial phase of HIV infection. The study fills a knowledge gap, as previously, the function of MAIT cells during this particular phase was not […]

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Injection of virus-delivered gene silencer blocks ALS degeneration, saves motor function

Writing in Nature Medicine, an international team headed by researchers at University of California San Diego School of Medicine describe a new way to effectively deliver a gene-silencing vector to adult amyotrophic lateral sclerosis (ALS) mice, resulting in long-term suppression of the degenerative motor neuron disorder if treatment vector is delivered prior to disease onset, and blockage of disease progression […]

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Autonomic nervous system appears to function well regardless of mode of childbirth

Late in pregnancy, the human body carefully prepares fetuses for the rigors of life outside the protection of the womb. Levels of cortisol, a stress hormone, ramp up and spike during labor. Catecholamines, another stress hormone, also rise at birth, helping to kick start the necessary functions that the baby will need to regulate breathing, heartbeat, blood pressure and energy […]

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