White matter changes in brain found in frontotemporal dementia

Areas of brain damage called white matter hyperintensities are commonly linked to vascular health problems. They have also been linked to Alzheimer’s disease. Now a new study has shown that white matter hyperintensities are also found in frontotemporal dementia. The study is published in the February 17, 2021, online issue of Neurology. Frontotemporal dementia, which often affects people under the […]

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The four dietary changes that may signal dementia – what to look for

Dementia is a progressive brain condition whereby parts of the brain become irreversibly damaged. There are many different causes of dementia, and many different types. The symptoms are dictated by the cause of dementia and the region of the brain affected. An uncommon form of dementia is frontotemporal dementia, which, as the name suggests, primarily affects the frontal and temporal […]

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RNA quality control system goes awry in frontotemporal lobar degeneration

Researchers at Osaka University have identified a fault in the RNA quality control system of cells that leads to the haywire production of toxic proteins in frontotemporal lobar degeneration and amyotrophic lateral sclerosis (FTLD/ALS). Their new study, published in the EMBO Journal, shows that an abnormality of the C9orf72 gene produces toxic proteins that hinder the cells’ ability to destroy […]

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