Curcumin nanosystems could be powerful COVID-19 therapeutics

With new variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerging, the coronavirus disease 2019 (COVID-19) pandemic is far from over. While the global vaccine rollout has moved at an impressive speed, the search for new safe, effective, and targeted therapies is still on. Now, a new study in Biomedicine and Pharmacotherapy reviews the potential for curcumin, a natural […]

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Nanoparticles elicit neutralizing antibodies to diverse SARS-CoV-2 variants

Spike-protein-based nanoparticle vaccine candidates were retained longer in follicular dendritic cells and showed higher germinal center reactions in lymph node follicles compared to soluble spike protein vaccine. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected hundreds of millions worldwide since its emergence more than a year ago. The virus has also been mutating throughout the pandemic, with several […]

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New covalent and non-covalent SARS-CoV-2 inhibitors discovered in silico

With the onset of the coronavirus disease 2019 (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), it came to light that there were no specific and highly effective preventive or therapeutic agents against this virus. The result has been an enormous amount of studies reporting the efficacy or otherwise of novel drug candidates or repurposed drugs […]

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Novavax COVID-19 vaccine shows 96.4% efficacy, less protection against variants

Fox News Flash top headlines for March 12 Fox News Flash top headlines are here. Check out what’s clicking on Foxnews.com. The Maryland-based biotech Novavax has announced its COVID-19 vaccine candidate has 96.4% efficacy against COVID-19 illness from the original strain, sliding to 86.3% against the U.K. variant and falling to 48.6% in South Africa amid circulation of another concerning coronavirus variant.  […]

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Believing in one’s own capabilities boosts personal resilience, shows study

The unpredictable nature of life during the coronavirus pandemic is particularly challenging for many people. Not everyone can cope equally well with the uncertainty and loss of control. Research has shown that while a large segment of the population turns out to be resilient in times of stress and potentially traumatic events, others are less robust and develop stress-related illnesses. […]

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Single-dose of BNT162b2 vaccine may not be protective without prior SARS-CoV-2 infection

Vaccine rollouts in many countries are bringing hope that the coronavirus disease 2019 (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), will come to an end in the foreseeable future. Several vaccines have shown high protective efficacy against SARS-CoV-2 infection or severe disease. Study: Effect of previous SARS-CoV-2 infection on humoral and T-cell responses to single-dose […]

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New combination treatment approach improves overall survival in mice with glioblastoma

Findings In a study of mice, researchers at the UCLA Jonsson Comprehensive Cancer Center have identified a new approach that combines an anti-psychotic drug, a statin used to lower high cholesterol levels, and radiation to improve the overall survival in mice with glioblastoma. Glioblastoma is one of the deadliest and most difficult-to-treat brain tumors. Researchers found the triple combination extended […]

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Extract of medicinal plant Artemisia annua interferes with replication of SARS-CoV-2 in vitro

Researchers in the United States have shown that extracts of an aromatic herb called Artemisia annua inhibit the replication of severe acute respiratory coronavirus (SARS-CoV-2) – the agent responsible for the current coronavirus disease 2019 (COVID-19) pandemic. Also known as “Sweet wormwood,” Artemisia annua (A. annua) is an herb from Asia that produces the antimalarial agent artemisinin. Study: Artemisia annua […]

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