Reports of Severe Covid or Death After Vaccination Are Rare, but Not Unexpected

No vaccine is ever 100 percent effective, experts say, stressing that the shots remain critical in reducing severe disease and death from the coronavirus. By Emily Anthes Over the last few months, a steady drumbeat of headlines has highlighted the astounding real-world effectiveness of the Covid-19 vaccines, especially the mRNA vaccines made by Pfizer-BioNTech and Moderna. The vaccines, study after […]

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Classification scheme developed for newly identified multiple sclerosis-like disease

Researchers in the Department of Neurology at Tohoku University, which is led by professor Masashi Aoki, have developed a classification scheme for neuromyelitis optica spectrum disorder, a rare autoimmune disease that until recently was thought to be a type of multiple sclerosis (MS). The new taxonomy for the disease replaces one borrowed from MS but which was inappropriate for what […]

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Chemical modification of RNA could play key role in polycystic kidney disease

A chemical modification of RNA that can be influenced by diet appears to play a key role in polycystic kidney disease, an inherited disorder that is the fourth leading cause of kidney failure in the U.S., UT Southwestern researchers report in a new study. The findings, published online today in Cell Metabolism, suggest new ways to treat this incurable condition. […]

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PLD3 gene contributes to risk of Alzheimer’s disease

A rare and controversial mutation in the phospholipase D3 (PLD3) protein—previously linked to Alzheimer’s disease—interferes with PLD3’s vital recycling function inside neurons. Matthew Schrag of Vanderbilt University Medical Center and colleagues report these new findings in a paper published April 8th in PLOS Genetics. About 1 percent of people with Alzheimer’s disease carry a specific mutation in their PLD3 gene. […]

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Alzheimer’s Disease: Everything You Need To Know

In case you didn’t already know, Alzheimer’s is a disease that robs people of their memory. At first, people have a hard time remembering recent events, though they might easily recall things that happened years ago. People with Alzheimer’s might forget their loved ones. They might forget how to dress, feed themselves, and use the toilet. This disease makes the […]

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Scientists identify genetic pathway that suppresses Lou Gehrig’s Disease

Professor Chunghun Lim and his research team in the Department of Biological Sciences unveiled a neuroprotective pathway that suppresses Lou Gehrig’s Disease (ALS). Nucleocytoplasmic transport (NCT) defects have been implicated in neurodegenerative diseases, such as C9ORF72-associated amyotrophic lateral sclerosis and frontotemporal dementia (C9-ALS/FTD). In this study, the research team has identified a neuroprotective pathway of like-Sm protein 12 (LSM12) and […]

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Racial disparities in heart disease, hypertension, and diabetes death rates

In the last 20 years, Black adults living in rural areas of the United States experienced high mortality rates due to diabetes, high blood pressure, heart disease and stroke compared to white adults. According to a research letter published in the Journal of the American College of Cardiology, racial disparities improved minimally in rural areas over the last two decades, […]

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Aspirin use for cardiovascular disease may reduce likelihood of COVID-19 infection

Aspirin is an established, safe, and low-cost medication in long-standing common use in prevention and treatment of cardiovascular diseases, and in the past a pain relief and fever reducing medication. The use of aspirin was very popular during the 1918 Spanish Influenza pandemic, several decades before in-vitro confirmation of its activity against RNA viruses. Studies showed that aspirin, in addition […]

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New study links protein causing Alzheimer’s disease with common sight loss

Newly published research has revealed a close link between proteins associated with Alzheimer’s disease and age-related sight loss. The findings could open the way to new treatments for patients with deteriorating vision and through this study, the scientists believe they could reduce the need for using animals in future research into blinding conditions. Amyloid beta (Ab) proteins are the primary […]

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