Research finds higher disease protection in fat cells in females

Research from the University of Cincinnati finds a higher presence of mitochondria in fat tissue in females. The research suggests this provides women protection against obesity and metabolic diseases. The study was published in Nature Metabolism. Mitochondria, explains Karthickeyan Chella Krishnan, Ph.D., assistant professor in the Department of Pharmacology and Systems Physiology in the UC College of Medicine, produce energy […]

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The C.D.C. Issues New School Guidance, With Emphasis on Full Reopening

The guidance acknowledges that many students have suffered from months of virtual learning. By Sheryl Gay Stolberg, Emily Anthes and Sarah Mervosh The Centers for Disease Control and Prevention released new guidance on Friday urging schools to fully reopen in the fall, even if they cannot take all of the steps the agency recommends to curb the spread of the coronavirus […]

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Cardiovascular disease: How signal proteins of the immune system regulate the development of atherosclerosis

Medical researchers at Ludwig-Maximilians-Universitaet (LMU) in Munich have uncovered how signal proteins of the immune system regulate the development of atherosclerosis. Atherosclerosis is one of the most common causes of death in Germany. The condition is characterized by the buildup of cholesterol and other fatty metabolites in the arterial wall directly below the endothelial cell layer, which is in direct […]

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Reports of Severe Covid or Death After Vaccination Are Rare, but Not Unexpected

No vaccine is ever 100 percent effective, experts say, stressing that the shots remain critical in reducing severe disease and death from the coronavirus. By Emily Anthes Over the last few months, a steady drumbeat of headlines has highlighted the astounding real-world effectiveness of the Covid-19 vaccines, especially the mRNA vaccines made by Pfizer-BioNTech and Moderna. The vaccines, study after […]

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Classification scheme developed for newly identified multiple sclerosis-like disease

Researchers in the Department of Neurology at Tohoku University, which is led by professor Masashi Aoki, have developed a classification scheme for neuromyelitis optica spectrum disorder, a rare autoimmune disease that until recently was thought to be a type of multiple sclerosis (MS). The new taxonomy for the disease replaces one borrowed from MS but which was inappropriate for what […]

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Chemical modification of RNA could play key role in polycystic kidney disease

A chemical modification of RNA that can be influenced by diet appears to play a key role in polycystic kidney disease, an inherited disorder that is the fourth leading cause of kidney failure in the U.S., UT Southwestern researchers report in a new study. The findings, published online today in Cell Metabolism, suggest new ways to treat this incurable condition. […]

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PLD3 gene contributes to risk of Alzheimer’s disease

A rare and controversial mutation in the phospholipase D3 (PLD3) protein—previously linked to Alzheimer’s disease—interferes with PLD3’s vital recycling function inside neurons. Matthew Schrag of Vanderbilt University Medical Center and colleagues report these new findings in a paper published April 8th in PLOS Genetics. About 1 percent of people with Alzheimer’s disease carry a specific mutation in their PLD3 gene. […]

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Alzheimer’s Disease: Everything You Need To Know

In case you didn’t already know, Alzheimer’s is a disease that robs people of their memory. At first, people have a hard time remembering recent events, though they might easily recall things that happened years ago. People with Alzheimer’s might forget their loved ones. They might forget how to dress, feed themselves, and use the toilet. This disease makes the […]

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Scientists identify genetic pathway that suppresses Lou Gehrig’s Disease

Professor Chunghun Lim and his research team in the Department of Biological Sciences unveiled a neuroprotective pathway that suppresses Lou Gehrig’s Disease (ALS). Nucleocytoplasmic transport (NCT) defects have been implicated in neurodegenerative diseases, such as C9ORF72-associated amyotrophic lateral sclerosis and frontotemporal dementia (C9-ALS/FTD). In this study, the research team has identified a neuroprotective pathway of like-Sm protein 12 (LSM12) and […]

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