Novel discovery describes the mechanisms of wound detection in the body

A new study from Vanderbilt University researchers has established a novel way to understand how the body discovers and responds to wounds. The research was led by graduate student James O’Connor and Professor Andrea Page-McCaw in the Department of Cell and Developmental Biology, and Shane Hutson, chair of the Department of Physics and Astronomy and professor of physics and biological […]

Read more

Discovery of unknown brain-repair process could lead to new epilepsy treatments

University of Virginia School of Medicine researchers have discovered a previously unknown repair process in the brain that they hope could be harnessed and enhanced to treat seizure-related brain injuries. Common seizure-preventing drugs do not work for approximately a third of epilepsy patients, so new and better treatments for such brain injuries are much needed. UVA’s discovery identifies a potential […]

Read more

Discovery of a new drug for diabetic retinopathy

A potentially effective treatment for diabetic retinopathy, a disease that swells and scars the retina, has been developed by an Université de Montréal scientist and investigator at Maisonneuve-Rosemont Hospital Research Centre (MRH-RC). Working with research scientist Pam Tsuruda of the San Francisco-based company UNITY Biotechnology, Przemyslaw (Mike) Sapieha published the results of the research project on mice Friday in the […]

Read more

Discovery of early plasma biomarkers for Alzheimer’s disease

A Quebec research team has discovered two early plasma markers to detect Alzheimer’s disease five years before its onset. The results of this recent study led by the doctoral student Mohamed Raâfet Ben Khedher and postdoctoral student Mohamed Haddad, directed by Professor Charles Ramassamy of the Institut national de la recherche scientifique (INRS), have been published in Alzheimer’s & Dementia: […]

Read more

New discovery on the activity and function of MAIT cells during acute HIV infection

In a new study published in Nature Communications, researchers at Karolinska Institutet show that mucosa-associated invariant T cells (MAIT cells) of the human immune system respond with dynamic activity and reprogramming of gene expression during the initial phase of HIV infection. The study fills a knowledge gap, as previously, the function of MAIT cells during this particular phase was not […]

Read more

Machine learning’s next frontier: Epigenetic drug discovery

Machine learning’s powerful ability to detect patterns in complex data is revolutionizing how we drive, how we diagnose disease and now, how we discover new drugs. Scientists at Sanford Burnham Prebys Medical Discovery Institute have developed a machine-learning algorithm that gleans information from microscope images—allowing for high-throughput epigenetic drug screens that could unlock new treatments for cancer, heart disease, mental […]

Read more

Discovery of mechanism behind precision cancer drug opens door for more targeted treatment

New research that uncovers the mechanism behind the newest generation of cancer drugs is opening the door for better targeted therapy. PARP inhibitors are molecular targeted cancer drugs used to treat women with ovarian cancer who have the BRCA1 and BRCA2 gene mutations. The drugs are showing promise in late-stage clinical trials for breast cancer, prostate cancer and pancreatic cancer […]

Read more

The cell discovery that could stop allergies

A new cell type that could stop allergies before they begin has been discovered by researchers at the Australian National University (ANU). The finding gives hope to people who live with a range of allergic conditions including asthma, eczema and life-threatening anaphylaxis. “By carefully studying the tonsils of children undergoing routine tonsillectomies, we identified a new cell type of the […]

Read more

New discovery in how mammals sense the cold could lead to new pain relief drugs

Researchers at UCL have shown for the first time that mammals detect different intensities of cold using distinct sensory neuron systems, a finding which could lead to the development of new drugs to treat cold pain. The study on mice, published in Proceedings of the National Academy of Sciences, set out to understand more about the two known sensory neuron […]

Read more
1 2