Diet impacts the sensitivity of gut microbiome to antibiotics, mouse study finds

Antibiotics save countless lives each year from harmful bacterial infections — but the community of beneficial bacteria that live in human intestines, known as the microbiome, frequently suffers collateral damage. Peter Belenky, an assistant professor of molecular microbiology and immunology at Brown University, studies ways to minimize this side effect, which can lead to C. diff infections and other life-threatening […]

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High-fat diets affect your brain, not just your physical appearance

Much research has pointed to how an unhealthy diet correlates to obesity, but has not explored how diet can bring about neurological changes in the brain. A recent Yale study has discovered that high-fat diets contribute to irregularities in the hypothalamus region of the brain, which regulates body weight homeostasis and metabolism. Led by Sabrina Diano, the Richard Sackler Family […]

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The role of a single molecule in obesity: Molecule mimics high-fat diet-induced signaling

A single cholesterol-derived molecule, called 27-hydroxycholesterol (27HC), lurks inside your bloodstream and will increase your body fat, even if you don’t eat a diet filled with red meat and fried food. That kind of diet, however, will increase the levels of 27HC and body weight. “We found 27HC directly affects white adipose (fat) tissue and increases body fat, even without […]

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Maximising alertness and productivity on the nightshift

If you’re one of Australia’s 1.4 million shiftworkers, eating at irregular times is just par for the course — but have you ever stopped to think about the impact this might have on your body? In a new research study by the University of South Australia, researchers have investigated whether altering food intake during the nightshift could optimise how shiftworkers […]

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Obese people outnumber smokers two to one

New figures from Cancer Research UK show that people who are obese now outnumber people who smoke two to one in the UK*, and excess weight causes more cases of certain cancers than smoking, as the charity urges Government action to tackle obesity. Almost a third of UK adults are obese** and, while smoking is still the nation’s biggest preventable […]

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Skinny self-image, heavy workouts in adolescence are warning signs, study shows: 22 percent of young men, 5 percent of young women engage in ‘disordered eating’ to bulk up

Adolescents who see themselves as puny and who exercise to gain weight may be at risk of so-called muscularity-oriented disordered eating behaviors, say researchers led by UCSF Benioff Children’s Hospitals. The researchers found that 22 percent of males and 5 percent of females ages 18-to-24 exhibit these disordered eating behaviors, which are defined as including at least one of the […]

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Phenols in cocoa bean shells may reverse obesity-related problems in mouse cells

Scientists may have discovered more reasons to love chocolate. A new study by researchers at the University of Illinois suggests that three of the phenolic compounds in cocoa bean shells have powerful effects on the fat and immune cells in mice, potentially reversing the chronic inflammation and insulin resistance associated with obesity. Visiting scholar in food science Miguel Rebollo-Hernanz and […]

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Achieving sugar reduction targets could cut child obesity and healthcare costs: But these benefits could be lost if goals are not fully met, warn researchers

Reducing the sugar content of certain foods by 2020, in line with UK government policy targets, could cut child obesity and related illness, and save the NHS in England £286 million over 10 years, suggests a study published by The BMJ today. But these benefits could be easily lost if the targets are not fully met, or if the programme […]

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Structure of the molecular machine that links carbohydrate and lipid metabolism

A research team led by dr. Kenneth Verstraete in the Unit for Structural Biology at the VIB-UGent Center for Inflammation Research has unraveled the three-dimensional structure and molecular mechanism of ATP citrate lyase (ACLY). This is a central metabolic enzyme — a protein that accelerates chemical reactions — important for the production of fatty acids and cholesterol in the human […]

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Thirty years of fast food: Greater variety, but more salt, larger portions, and added calories

Despite the addition of some healthful menu items, fast food is even more unhealthy for you than it was 30 years ago. An analysis of the offerings at 10 of the most popular US fast-food restaurants in 1986, 1991, and 2016, published in the Journal of the Academy of Nutrition and Dietetics, demonstrates that fast-food entrees, sides, and desserts increased […]

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