Vaccine development software shows promise in influenza effort, could help defeat coronavirus

A novel computer algorithm that could create a broadly reactive influenza vaccine for swine flu also offers a path toward a pan-influenza vaccine and possibly a pan-coronavirus vaccine as well, according to a new paper published in Nature Communications. “This work takes us a step closer to a pan-swine flu virus vaccine,” said Bette Korber, a computational biologist at Los […]

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New insight to Campylobacter sensor structures could lead to targeted antibiotic development

Researchers from the Institute of Glycomics have identified a novel bacterial sensor in Campylobacter species that enable the pathogenic cells to find suitable host cells. The findings have been published in Science Signalling. Campylobacter bacteria are the leading cause of food-borne illness, contributing to enteritis and other gastrointestinal distress we commonly identify as “food poisoning.” About one percent of the […]

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Study profiles immune cells fighting COVID-19, may help guide next-gen vaccine development

Even as the first vaccines for SARS-CoV-2, the virus that causes COVID-19, are being distributed, scientists and clinicians around the world have remained steadfast in their efforts to better understand how the human immune system responds to the virus and protects people against it. Now, a research team—led by Johns Hopkins Medicine and in collaboration with ImmunoScape, a U.S.-Singapore biotechnology […]

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Immune responses during embryo development could increase risk of schizophrenia

Past research has often highlighted the effects that immune activation in pregnant women can have on the development of human embryos, for instance increasing the risk of a child developing psychiatric disorders later in life. The neural mechanisms underpinning these effects, however, remain largely unclear. Researchers at New York Medical College have recently carried out a study investigating the impact […]

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Component of human breast milk enhances cognitive development in babies

Maternal factors, such as breast milk, have been shown to affect a baby’s development, and previous animal studies have determined that a carbohydrate, the oligosaccharide 2’FL found in maternal milk, positively influences neurodevelopment. Now, in the first study done in humans, investigators at Children’s Hospital Los Angeles in collaboration with the University of California, San Diego, have shown that 2’FL […]

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The brain may need iron for healthy cognitive development

Iron levels in brain tissue rise during development and are correlated with cognitive abilities, according to research in children and young adults recently published in JNeurosci. Future work could lead to iron supplementation as an intervention for atypical cognitive development. Brain cells stay healthy in part by storing iron. It is most concentrated in the basal ganglia, a brain region […]

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Some child development milestones may be set too early

CDC guidelines say most children reach a milestone by a certain age, but new data shows that “most” may mean over 99% or barely half. A new Boston University School of Public Health (BUSPH) study published in the journal Pediatrics provides more specific data on what ages young children reach different developmental milestones. Guidelines from the CDC say “most children” […]

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Novel model for studying intestinal parasite could advance vaccine development

The intestinal parasite Cryptosporidium, which causes a diarrheal disease, is very good at infecting humans. It’s the leading cause of waterborne disease from recreational waters in the United States. Globally, it’s a serious illness that can stunt the growth of, or even kill, infants and young children. And people with compromised immune systems, such as those with HIV/AIDS, are also […]

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Do minerals play a role in development of multiple sclerosis?

Some studies have suggested that minerals such as zinc and iron may play a role in how multiple sclerosis (MS) progresses, once people have been diagnosed with it. But little was known about whether zinc, iron and other minerals play a role in the development of the disease. A new study shows no link between dietary intake of several minerals […]

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