MRI-identified damage tied to patient-reported RA function

(HealthDay)—There is a consistent association between magnetic resonance imaging (MRI) findings of damage in the wrist and hand and self-reported loss of function in patients with established rheumatoid arthritis (RA) in sustained clinical remission, according to a study recently published in the International Journal of Rheumatic Diseases. Daniel Glinatsi, M.D., Ph.D., from the Copenhagen Center for Arthritis Research at Rigshospitalet […]

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Two enzymes control liver damage in NASH, study shows

As much as 12 percent of adults in the United States are living with nonalcoholic steatohepatitis (NASH), an aggressive condition that can lead to cirrhosis or liver cancer. After identifying a molecular pathway that allows NASH to progress into liver cell death, University of California San Diego School of Medicine researchers were able to halt further liver damage in mouse […]

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New clues found to help protect heart from damage after heart attack

Studying mice, scientists have shown that boosting the activity of specific immune cells in the heart after a heart attack can protect against developing heart failure, an invariably fatal condition. Patients with heart failure tire easily and become breathless from everyday activities because the heart muscle has lost the ability to pump enough blood to the body. The study, by […]

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Lenalidomide may delay onset of myeloma-related bone, organ damage

The largest randomized trial in asymptomatic patients with smoldering multiple myeloma suggests that lenalidomide, a cancer drug, may delay the onset of bone and other myeloma-related organ damage. Results of the study, which was conducted by the Eastern Cooperative Oncology Group and funded by the National Cancer Institute, were published Friday, Oct. 25, in the Journal of Clinical Oncology. “Our […]

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Vitamin E found to prevent muscle damage after heart attack

Heart attack is a leading cause of death worldwide and new treatment strategies are highly sought-after. Unfortunately lasting damage to the heart muscle is not uncommon following such an event. Published in Redox Biology, the pre-clinical study sheds new light on the potential of the acute therapy with α-TOH (vitamin E) in patients presenting with heart attack, and may ultimately […]

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Cell-free DNA detects pathogens and quantifies damage

A common problem in diagnosing infectious disease is that the presence of a potential pathogen in the body does not necessarily mean the patient is sick. This can be particularly challenging for the treatment of organ transplant recipients, who often grapple with infection as well as complications related to immunosuppression. A new Cornell study, “A Cell-Free DNA Metagenomic Sequencing Assay […]

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Gut microbiota linked to organ damage in patients with sepsis

Sepsis is a serious condition that can result in organ failure and even death. A novel human study published in The FASEB Journal demonstrates for the first time that the gut microbiota of patients with sepsis plays a major role in organ damage. To conduct the experiment, researchers first compared the fecal microbial composition of two human groups: people who […]

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Antibiotic use can increase nerve damage risk

Research from the University of Dundee has shown that a commonly used class of antibiotics may increase a patient’s risk of suffering a serious and potentially permanent form of nerve damage by almost 50 percent. Peripheral neuropathy has long been recognised as a potential side effect of fluoroquinolone antibiotics but it was not known how strong this association was and […]

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Pig experiment raises ethical questions around brain damage

The brain is more resilient than previously thought. In a groundbreaking experiment published in this week’s issue of Nature, neuroscientists created an artificial circulation system that successfully restored some functions and structures in donated pig brains—up to four hours after the pigs were butchered at a USDA food processing facility. Though there was no evidence of restored consciousness, brains from […]

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These sleep myths harm health

Many people claim they would get by on five or less hours of sleep, snoring is harmless or alcohol to help fall asleep. These are excuses to justify bad habits, or to make these things actually? In the journal Sleep Health researchers reported that these widespread myths are not harmless. Sleep medicine experts at the New York University School of […]

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