Amy Dowden health: ‘My body couldn’t cope’ Strictly star on her life-altering condition

Amy Dowden, 28, has regularly appeared on Strictly Come Dancing since 2017. the star has devoted her life to dancing but her passionate pursuit has not come easy. In may this year, Amy divulged on ITV’s This Morning that she’d been living with Crohn’s disease since she was a child. She revealed she first experienced symptoms of the condition aged […]

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What drives inflammation in type 2 diabetes? Not glucose, says new research

To date, the underlying causes of inflammation in obesity and type 2 diabetes mellitus (T2DM) have been poorly understood, which has hampered efforts to develop treatments to prevent complications from a disease that is the third leading cause of death in the United States. But new research at the University of Kentucky shows that changes to mitochondria — the powerhouse […]

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Potential treatment target for Crohn’s disease

There is no cure for the more than 1.6 million people in the United States living with Crohn’s disease (CD) and its symptoms, including abdominal pain, intestinal distress and severe weight-loss. CD is a form of inflammatory bowel disease (IBD) in which the body’s own immune system attacks the gastrointestinal tract, and treatment is focused on controlling the symptoms of […]

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Jeff Hordley health: Emmerdale’s Cain Dingle on chronic condition – major sign to look for

Most people know Jeff Hordley for his portrayal of Cain Dingle in the popular soap opera Emmerdale. What the public may not realise is that he was diagnosed with Crohn’s disease a couple of years before his big break. The life-long condition causes parts of the digestive system to become enflamed. Jeff has spoken out in the past about what […]

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A deep-dive into the impact of arthritis drugs on gene expression: New analytical approach could serve as powerful tool to evaluate and compare treatments

A new computational framework has revealed key differences between four rheumatoid arthritis medications and their impact on biological pathways in mice. Niki Karagianni of Biomedcode Hellas SA, Greece, and colleagues present their new approach and findings in PLOS Computational Biology. People with rheumatoid arthritis often receive medications that target and inhibit Tumor-Necrosis Factor (TNF), a protein involved in the painful […]

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Exercise helps prevent cartilage damage caused by arthritis

Exercise helps to prevent the degradation of cartilage caused by osteoarthritis, according to a new study from Queen Mary University of London. The researchers show for the first time how mechanical forces experienced by cells in joints during exercise prevent cartilage degradation by suppressing the action of inflammatory molecules which cause osteoarthritis. The study, published in the journal Osteoarthritis and […]

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Microglia react distinctively during inflammation: LIH scientists provide new insights into function and heterogeneity of brain immune cells

The NorLux Neuro-Oncology Laboratory at LIH’s Department of Oncology conducts research on brain diseases, with a special emphasis on glioma biology, drug resistance and systems approaches. Within this research unit, Dr. Alessandro Michelucci focuses on the role of glial cells and inflammatory responses. Jointly with team member Dr. Carole Sousa and collaborating research groups from LIH and the University of […]

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Novel anti-inflammatory bacterial protein discovered: Newly discovered protein alleviates intestinal inflammation and septic shock in an animal model

Researchers at the University of Oregon have identified a novel protein secreted by a common gut bacterium in zebrafish that reduces inflammation in the gut and delays death by septic shock. By examining how the protein, Aeromonas immune modulator (AimA), mutually benefits both the bacteria and their larval zebrafish hosts, the research team’s experiments shed light on how animals and […]

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