Vaccination protects against COVID-19 related hospitalization in patients with and without comorbidity

Coronavirus disease 2019 (COVID-19) has spread to almost every country in the world, causing over five million deaths and forcing many governments to enact costly and restrictive lockdown measures. These have included mandatory mask-wearing, the closing of public spaces, and even full lockdowns/stay-at-home orders. Study: Vaccine effectiveness against COVID-19 related hospital admission in the Netherlands: a test-negative case-control study. Image […]

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Potential therapeutic targets of hydrogen for treatment of the COVID-19

Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has led to the ongoing global pandemic. The pathophysiological process of COVID-19 is an excessive inflammatory response in the host after the viral infection. Study: Molecular Hydrogen: A Promising Adjunctive Strategy for the Treatment of the COVID-19. Image Credit: ker_vii/ Shutterstock Multiple therapies have been tested to […]

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New Delta sublineage shows no additional resistance to neutralization

Coronavirus disease 2019 (COVID-19) has caused over five million deaths and has spread to nearly every country in the world. When the disease first emerged, many countries were forced to enact costly and restrictive measures to prevent the spread of the disease, including mandatory face masks in public spaces, social distancing, and even stay-at-home orders and lockdowns. While mass vaccination […]

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APOL1 variant risk may extend to poorer outcomes from SARS-CoV-2 infection

The rapid outbreak of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in the coronavirus disease 2019 (COVID-19) pandemic. COVID-19 has caused widespread havoc claiming more than 5 million lives worldwide. There is a wide range of hospitalization rates and mortality risks associated with COVID-19. Black ethnic populations are at a disproportionately high risk of hospitalization or death […]

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Study suggests increased pediatric COVID-19 hospitalizations related to increased Delta variant incidence

The coronavirus disease 2019 (COVID-19) pandemic has been a heavy blow to the world's health and wealth but is generally thought to have spared children. It is necessary to take a fresh look at it, however, in light of the fact that pediatric vaccination with COVID-19 vaccines is still not generally approved while more and more children are returning to […]

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Factors predicting cognitive symptoms in long COVID

With the coronavirus disease 2019 (COVID-19) pandemic, most infections are asymptomatic or mild, but a significant minority develop severe symptoms. Some earlier studies have indicated that initial disease severity predicts the risk of long-term symptoms, as well as their intensity. Moreover, limb weakness is one of several acute symptoms that are associated with more severe long-haul COVID-19. Study: COVCOG 1: […]

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Chemical substance may specifically inhibit both SARS-CoV-2 proteases and human protease

Both severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV) of the Coronaviridae family rapidly spread among humans can cause fatal respiratory diseases. But these viruses never reached pandemic scale. However, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) quickly reached the pandemic scale. More than 242 million infections and 4.9 million deaths associated with coronavirus 2019 […]

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COVID-19 vaccinations associated with reduction of COVID-19 infections and deaths among Medicare beneficiaries

Coronavirus disease 2019 (COVID-19) vaccinations were introduced in the United States in December 2020. Initially, COVID-19 vaccines were made available to nursing home residents and healthcare workers but were then rolled out differently according to state, but mainly prioritizing the elderly. Study: Associations Between County-level Vaccination Rates and COVID-19 Outcomes Among Medicare Beneficiaries. Image Credit: CameraCraft/ Shutterstock The first vaccine […]

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The role of ZBP1 in promoting SARS-CoV-2-induced cytokine expression

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causal agent of the coronavirus disease 2019 (COVID-19) pandemic. This virus causes mild to severe disease, and to date, it has claimed more than 4.8 million lives worldwide. In the case of severe disease, scientists revealed that over-reaction of the immune system leads to a cytokine storm. Excessive cytokine levels correlate […]

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How effective are COVID-19 vaccines against SARS-CoV-2 variants of concern?

As of 29 September 2021, there have been more than 232 million cases and 4.76 million deaths recorded worldwide as a result of coronavirus 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).  A number of vaccines have been developed to cope with this pandemic, and they have proven highly effective in observational and randomized trials (RCTs). The […]

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