Russia starts clinical trials of COVID-19 vaccine

Clinical trials of a Russian coronavirus vaccine have started Wednesday, the Health Ministry said in a statement. Two forms of the vaccine developed by the Moscow-based Gamaleya research institute—liquid and powder for injections—will be tested on two groups of volunteers, 38 people each, the statement said. The participants will be isolated in two Moscow hospitals. “Running clinical trials in the […]

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First clinical trial with genetically modified malaria vaccine completed

In an innovative study, Radboudumc and LUMC jointly tested a candidate vaccine based on a genetically weakened malaria parasite. The results of this clinical trial, published in Science Translational Medicine, show that the vaccine is safe and elicits a defense response against a malaria infection. Malaria is a major infectious disease, caused by a parasite with a complicated life cycle […]

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How to carry out rapid clinical research in combating COVID-19

Amid ongoing efforts to tackle the coronavirus pandemic, some European countries have begun to take cautious steps to ease lockdown restrictions while others brace for worse. Like several ongoing EU-funded research projects that have reoriented their work to help combat the outbreak, the PREPARE project is responding to COVID-19 by rapidly assessing Europe’s preparedness and deploying vital clinical research. Through […]

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Select few cancer patients enroll in potentially life-extending clinical trials

Patient enrollment in clinical trials as the first course of treatment after cancer diagnosis is low, despite the fact that enrollment may increase life expectancy, according to researchers at Penn State. They also found that white males with private health insurance and metastatic cancers treated at academic medical centers are more likely than other groups to enroll in clinical trials. […]

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Telehealth helps one hospital reduce ER overflow hours from 1,700 to 148

Gastonia, North Carolina-based, 435-bed CaroMont Regional Medical Center is the anchor facility of a five-county, two-state, not-for-profit health system and value-based care provider, CaroMont Health. The medical center features a Level III trauma center. THE PROBLEM The hospital has approximately 250,000 patient encounters every year, and because of its location in the growing Charlotte region, continues to experience increases in […]

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First-ever US clinical trial of engineered iPSC-derived cell therapy for blood cancer

A new cancer clinical trial has opened at the M Health Fairview University of Minnesota Medical Center that leverages the groundbreaking research on stem cells and natural killer (NK) cells done at the Masonic Cancer Center and applies it to attack acute myeloid leukemia (AML) and B-cell lymphoma. The first-of-its-kind NK cell cancer immunotherapy, called FT516, is manufactured from a […]

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Cloud-enabled tumor board review enables faster insights than traditional methods

The conventional tumor board may soon be a thing of the past. Tumor boards typically comprise practitioners from multiple backgrounds, who meet to weigh a wide range of options for potential oncology treatments, study gene sequencing and assess patients’ suitability for clinical trials. They’re essential parts of the care process. But getting oncologists, pathologists, patient advocates and others together in […]

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UK urine test that can detect early-stage pancreatic cancer starts clinical study

A urine test that can detect early stage pancreatic cancer has reached the final stage of validation before being developed for use with patients. If successful, this non-invasive urine test would be the first in the world to help clinicians detect the highly lethal cancer at an early stage—enabling many more people to have surgery to remove their tumor, which […]

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