Clinical trial suggests convalescent plasma may improve survival with severe COVID-19

A randomized double-blind controlled trial of convalescent plasma for adults hospitalized with severe COVID-19 found that mortality at 28 days in the treatment arm was half the rate seen in the control arm (12.6% vs. 24.6%), although treatment was not associated with other improvements in clinical status. The study was led by investigators from the Center for Infection and Immunity […]

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Pfizer and Moderna vaccines are powerfully effective against Covid-19, a C.D.C. analysis confirmed.

By Emily Anthes The Pfizer-BioNTech and Moderna coronavirus vaccines are 94 percent effective at preventing symptomatic Covid-19 illness, according to a new study of more than 1,800 health care workers in the United States. The research, which the Centers for Disease Control and Prevention released on Friday, provides yet more evidence that the vaccines are working well even outside controlled […]

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At MemorialCare, digital health program enables turnaround for depression patients

MemorialCare Health System, based in Fountain Valley, California, is always looking for ways to help its community by providing meaningful health-and-wellness services. THE PROBLEM With the onset of the COVID-19 pandemic and subsequent isolating effects of lockdowns and social distancing, MemorialCare began seeing an influx of mental health and substance use disorder patients within the community and beyond. This increase, […]

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The M*A*S*H model of care and pushing IT to the limit – lessons from a tough 12 months

The past year has been like no other for healthcare provider organization executives. They have been put to the test, and the successful have survived intact, with many lessons learned along the way. Today, Healthcare IT News presents the latest in its feature story series talking with healthcare C-suite officers and other health IT leaders about the healthcare information technology […]

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Clinical trial: Using MRI for prostate cancer diagnosis equals or beats current standard

The results of a Phase III randomized clinical trial have shown that when it comes to detecting clinically significant prostate cancer, Magnetic Resonance Imaging (MRI) with targeted biopsies (MRI-TBx) matches the current standard and brings a multitude of advantages. The PRostate Evaluation for Clinically Important Disease: MRI vs Standard Evaluation Procedures (PRECISE) study will help to make prostate cancer diagnosis […]

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Britain Opts for Mix-and-Match Vaccinations, Confounding Experts

Amid a sputtering vaccine rollout and fears of a new and potentially more transmissible variant of the coronavirus, Britain has quietly updated its vaccination playbook to allow for a mix-and-match vaccine regimen. If a second dose of the vaccine a patient originally received isn’t available, or if the manufacturer of the first shot isn’t known, another vaccine may be substituted, […]

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F.D.A. Advisory Panel Gives Green Light to Pfizer Vaccine

Pfizer’s Covid-19 vaccine passed a critical milestone on Thursday when a panel of experts formally recommended that the Food and Drug Administration authorize the vaccine. The agency is likely to do so within days, giving health care workers and nursing home residents first priority to begin receiving the first shots early next week. The F.D.A.’s vaccine advisory panel, composed of […]

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INOVIO Doses First Subject in Phase 2 Segment of its INNOVATE Phase 2/3 Clinical Trial for INO-4800, its DNA Medicine to Prevent COVID-19

PLYMOUTH MEETING, Pa., Dec. 7, 2020 /PRNewswire/ — INOVIO (NASDAQ: INO), a biotechnology company focused on bringing to market precisely designed DNA medicines to treat and protect people from infectious diseases and cancer, today announced it has dosed its first subject in a Phase 2 clinical trial evaluating DNA medicine INO-4800, its COVID-19 vaccine candidate, as part of its Phase 2/3 clinical […]

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Researchers examine whether online physician reviews indicate clinical outcomes

Online consumer reviews play an important role in almost every consumer industry—from dining and shopping to travel and technology. But what do online reviews of physicians tell consumers? In a new study, researchers from The University of Texas at Dallas investigated whether patient-generated online reviews of physicians accurately reflect the quality of care. “Many patients use online reviews of physicians […]

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Study details strategies to address barriers keeping older adults out of clinical trials

A City of Hope-led study revealed little effort has been made to improve older adult representation in clinical trials of new cancer drugs, even when the treatment is aimed at a disease that disproportionately affects this age group. “There is currently no incentive to establish real-world effectiveness among older adults. Older adults need a seat at the table,” said Mina […]

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