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The results of a new patient survey by the British Liver Trust reveal that over half of chronic liver disease patients say they’ve had procedures cancelled or delayed due to the COVID-19 pandemic. The findings reflect the worrying situation that many clinically extremely vulnerable patients find themselves in as we head into the winter months – a time when pressure […]
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Over a year since the first case of the SARS-CoV-2 pandemic, fast advances in vaccine development have given the world a fighting chance against the coronavirus. SARS-CoV-2 vaccines have become leading instruments against severe health effects associated with COVID-19 disease. SARS-CoV-2 vaccines reduce severe disease and improve survival of infected patients. Their impact has been seen in developed countries where […]
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The Food and Drug Administration has approved difelikefalin for treatment of moderate to severe pruritus associated with chronic kidney disease in adults undergoing hemodialysis, the first agent approved from a novel class of kappa opioid receptor agonists. Some nephrologists welcomed the Aug. 23 approval of this new option for treating pruritus, a relatively common and often hard-to-resolve complication of dialysis […]
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Dapagliflozin (Forxiga) has been approved for use in the European Union to treat adults with chronic kidney disease who do not have diabetes. It is the first agent from the sodium-glucose cotransporter 2 inhibitor class to receive this designation in Europe. The approval follows the approval of the drug by the US Food and Drug Administration in April (in the […]
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Patients with inflammatory bowel diseases (IBD) do not appear to have increased risk of side effects from the Pfizer or Moderna COVID-19 vaccines, according to a recent Cedars-Sinai study published online and upcoming in print in the American Journal of Gastroenterology. In fact, those being treated with advanced immune-modifying therapies may experience them less often than the general population. IBDs, […]
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Today, the U.S. Food and Drug Administration approved Farxiga (dapagliflozin) oral tablets to reduce the risk of kidney function decline, kidney failure, cardiovascular death and hospitalization for heart failure in adults with chronic kidney disease who are at risk of disease progression. Chronic kidney disease is an important public health issue, and there is a significant unmet need for […]
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A national study of 20,000 patients conducted by RCSI University of Medicine and Health Sciences and the HSE Health Protection Surveillance Centre (HPSC) has identified the underlying conditions that are associated with more severe outcomes from COVID-19 in an Irish setting. The research, which has been published in The Lancet Regional Health – Europe, will help inform national public […]
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Researchers from Kumamoto University (Japan) have found that the anti-diabetic drug metformin significantly prolongs the survival of mice in a model that simulates the pathology of non-diabetic chronic kidney disease (ND-CKD) by ameliorating pathological conditions like reduced kidney function, glomerular damage, inflammation and fibrosis. Metformin's mechanism is different from existing therapeutics which only treat symptoms, such as the blood pressure […]
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People with Crohn's disease are typically treated with powerful anti-inflammatory medications that act throughout their body, not just in their digestive tract, creating the potential for unintended, and often serious, side effects. New research from the lab of Mark Sundrud, PhD, at Scripps Research, Florida suggests a more targeted treatment approach is possible. Crohn's disease develops from chronic inflammation in […]
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Chronic side effects among melanoma survivors after treatment with anti-PD-1 immunotherapies are more common than previously recognized, according to a study published March 25 in JAMA Oncology. The chronic complications, which occurred in 43% of patients, affected the joints and endocrine system most commonly, and less often involved salivary glands, eyes, peripheral nerves and other organs. These complications may be […]
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