Chronic migraine sufferers to get first new drug in 20 years

Chronic migraine sufferers are given fresh hope of getting rid of their crippling headaches with first new drug in 20 years New drug self-injected at home will benefit 10,000 people suffering migraines Fremanezumab was developed by UK scientists over three decades In trials the drug has reduced the frequency, severity and duration of migraines Lead researcher called the introduction of […]

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Media overrepresent drug treatments for chronic pain

Media reports on chronic pain are focusing on treatments involving opioids and cannabis at the expense of best practice non-drug treatments, researchers have found. Chronic pain, defined as persistent or recurring pain present for more than three months, is the leading cause of disability worldwide and affects one in five New Zealanders. The researchers analyzed 240 news articles on chronic […]

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Using gene therapy to treat chronic traumatic encephalopathy

A new study shows the feasibility of using gene therapy to treat the progressive neurodegenerative disorder chronic traumatic encephalopathy (CTE). The study, which demonstrated the effectiveness of direct delivery of gene therapy into the brain of a mouse model of CTE, is published in Human Gene Therapy. Ronald Crystal and colleagues from Weill Cornell Medical College, New York, NY, coauthored […]

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Yoga and physical therapy as treatment for chronic lower back pain also improves sleep

Yoga and physical therapy (PT) are effective approaches to treating co-occurring sleep disturbance and back pain while reducing the need for medication, according to a new study from Boston Medical Center (BMC). Published in the Journal of General Internal Medicine, the research showed significant improvements in sleep quality lasting 52 weeks after 12 weeks of yoga classes or 1-on-1 PT, […]

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Health care professionals consider ‘lifestyle medicine’ to address various chronic illnesses

As more options become available to pursue a healthy lifestyle, from dietary choices to exercise plans to preventative medicine and other advances, one organization—and one South Florida doctor in particular—is leading a movement toward “lifestyle medicine.” The American College of Lifestyle Medicine hosted its annual conference in Orlando recently where health care professionals from around the world convened to discuss […]

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Molecular link between chronic pain and depression revealed

Researchers at Hokkaido University have identified the brain mechanism linking chronic pain and depression in rats. Their research, which was recently published in the Journal of Neuroscience, could lead to the development of new treatments for chronic pain and depression. “Clinicians have known for a long time that chronic pain often leads to depression, however the brain mechanism for this […]

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Researchers find fecal marker could help diagnose early signs of chronic gut conditions

Small molecules found in fecal matter could provide clues to the early inflammation found in chronic gut conditions, such as intestinal bowel disease (IBD), and serve as new biomarkers for diagnosis, according to a study led by the Institute for Biomedical Sciences at Georgia State University. The researchers found that fecal miRNA, small nucleic acid sequences, could be used as […]

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SIRT1 plays key role in chronic myeloid leukemia to aid persistence of leukemic stem cells

Patients with chronic myeloid leukemia can be treated with tyrosine kinase inhibitors. While these effective drugs lead to deep remission and prolonged survival, primitive leukemia stem cells resist elimination during the remission and persist as a major barrier to cure. As a result, the majority of patients with chronic myeloid leukemia, or CML, require indefinite inhibitor treatment to prevent disease […]

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Chronic kidney disease of undetermined causes described originally in Central America and Sri Lanka

Chronic kidney disease of undetermined causes (CKDu), initially reported among agricultural communities in Central America and Sri Lanka, is also present in India, particularly in Southern rural areas, and could be common in other tropical and subtropical rural settings. These are the main conclusions of a new study published in BMJ Open. CDKu is considered an epidemic in Central America […]

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