Statins reduce COVID-19 severity, likely by removing cholesterol that virus uses to infect

There are no Food and Drug Administration (FDA)-approved treatments for COVID-19, the pandemic infection caused by a novel coronavirus. While several therapies are being tested in clinical trials, current standard of care involves providing patients with fluids and fever-reducing medications. To speed the search for new COVID-19 therapies, researchers are testing repurposed drugs—medicines already known to be safe for human […]

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Best supplements for cholesterol: Three of the best supplements to help lower your levels

Cholesterol is a waxy, fat-like substance that’s found in all the cells in the body. The liver makes cholesterol, and it is also in some foods, such as meat and dairy products. The body needs some cholesterol to work properly. However, having too much of the substance puts a person at serious risk of potentially life-threatening conditions such as heart […]

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Genetic discovery linked to rare eye disease

John A. Moran Eye Center physician-researcher Paul S. Bernstein, MD, PhD, and his patients at the University of Utah played a key role in the recent discovery of the first genetic cause for a rare eye disease. Macular telangiectasia type 2 (MacTel) affects about one in 5,000 people, causing a gradual loss of central vision, typically after age 40. As […]

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High-fat diets affect your brain, not just your physical appearance

Much research has pointed to how an unhealthy diet correlates to obesity, but has not explored how diet can bring about neurological changes in the brain. A recent Yale study has discovered that high-fat diets contribute to irregularities in the hypothalamus region of the brain, which regulates body weight homeostasis and metabolism. Led by Sabrina Diano, the Richard Sackler Family […]

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European guidelines on lipid control advocate ‘lower is better’ for cholesterol levels

Low-density lipoprotein (LDL) cholesterol levels should be lowered as much as possible to prevent cardiovascular disease, especially in high and very high risk patients. That’s one of the main messages of the European Society of Cardiology (ESC) and European Atherosclerosis Society (EAS) Guidelines on dyslipidaemias published online today in European Heart Journal and on the ESC website. Cardiovascular disease (CVD) […]

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Childhood cholesterol, blood pressure, weight and smoking predict adult heart disease

The first reliable evidence of a link between major cardiovascular risk factors in children — serum cholesterol, blood pressure, body mass index (BMI), and smoking — with cardiovascular disease in adults is presented today at ESC Congress 2019 together with the World Congress of Cardiology. The study highlights the need to lay the foundations for heart health early in life. […]

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The role of a single molecule in obesity: Molecule mimics high-fat diet-induced signaling

A single cholesterol-derived molecule, called 27-hydroxycholesterol (27HC), lurks inside your bloodstream and will increase your body fat, even if you don’t eat a diet filled with red meat and fried food. That kind of diet, however, will increase the levels of 27HC and body weight. “We found 27HC directly affects white adipose (fat) tissue and increases body fat, even without […]

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Blood pressure recording over 24 hours is the best predictor of heart and vascular disease

High blood pressure is the most important treatable risk factor for diseases of the heart and the arterial system. Blood pressure recorded over 24 hours predicts these complications more accurately than blood pressure measured on a single occasion. That is the conclusion of an international study coordinated by Professors Jan A. Staessen and Zhen-Yu Zhang of KU Leuven in Belgium. […]

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