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Berzosertib deprives cancer cells of the immune system Surprisingly positive results in the treatment of advanced tumors were achieved in a recent study using a drug from a new drug class. The substance called “Berzosertib” disabled specifically the repair of DNA damage in cancer cells, whereupon they die off. In the case of each of the second Participants of the […]
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As COVID-19 restrictions loosen this summer, Canadians will spend more time outdoors and make the most of the sunshine. A new study from McGill University suggests why men may be more genetically prone to develop skin cancer. The research led by Professor Ian Watson of McGill’s Goodman Cancer Research Centre (GCRC), published in the journal Nature Cancer, identified three genes […]
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For years, researchers have known that men of African ancestry are at greater risk of developing prostate cancer with research suggesting that inherited factors may contribute to their greater risk. Now, a new USC study published in European Urology is the first to identify an inherited genetic variant associated with higher risk of prostate cancer in men of African descent […]
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In an international trial led by researchers at The University of Texas MD Anderson Cancer Center, treatment with MK-6482, the small molecule inhibitor of hypoxia-inducible factor (HIF)-2a was well tolerated and resulted in clinical responses for patients with von Hippel-Lindau disease (VHL)-associated renal cell carcinoma (RCC). The results of the Phase II trial were shared today in an oral presentation […]
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For the past 70 years, the best indicator of life expectancy for a patient with glioblastoma (GBM)—the most common and the most aggressive brain cancer—has simply been age at diagnosis. Now, an international team of scientists has experimentally validated a predictor that is not only more accurate but also more clinically relevant: a pattern of co-occurring changes in DNA abundance […]
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May is skin cancer awareness month and one Kelowna physician is taking the opportunity to warn people about of the dangers of Melanoma. “Hey James, how are you doing?” asks Dr. Ben Wiese of the Kelowna Skin Cancer Clinic. “Come in have a seat,” Wiese motions to his patient James Wren. It’s Melanoma Monday and Wren is being checked over […]
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Most ovarian cancer starts in fallopian tubes. Then it sloughs from its site of origin and floats around in fluid until finding new sites of attachment. It’s not easy for cancer cells to survive away from their moorings. Observations by ovarian cancer doctors at University of Colorado Cancer Center and elsewhere hint at how they might do it: These doctors […]
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Following a cancer diagnosis, patients often ask many questions about their treatment and possible side effects. One area that is often overlooked is sexual health, which experts say is important to talk about to ensure quality of life. Dr. Jacqueline Thielen, a Mayo Clinic general internal medicine physician, says it’s normal for patients to experience changes during and after cancer […]
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The key to effective cures for cancers is to find weak points of cancer cells that are not found in non-cancer cells. Researchers at the Tokyo Metropolitan Institute of Medical Science found that cancerous and non-cancerous cells depend on different factors for survival when their DNA replication is blocked. Drugs that inhibited the survival factor required by cancer cells would […]
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Few heartbreaks are as devastating as when a beloved family dog falls ill with cancer. But a new research paper could spur development of more and better treatments for a canine companion who has a brain tumor—because it’s possible that those same therapies will help human kids, too. Dogs’ brain cancers are genetically akin to those found in children, a […]
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