One’s internal clock could be targeted to prevent or slow the progression of breast cancer

City of Hope scientists have identified an unlikely way to potentially prevent or slow the progression of aggressive breast cancer: target one’s internal clock. Often taken for granted, the circadian rhythm is gaining traction as a potential catalyst or brake for the onset of disease. For example, studies have shown that women who take frequent night shifts have disrupted internal […]

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New insight into immune cell behavior offers opportunities for cancer treatment

An international group of scientists has discovered that certain cells of our immune system—the so-called T cells—communicate with each other and work together as a team. To fight an infection they stimulate each other’s growth, but at the same time, they inhibit each other when there is a surplus of T cells. That insight offers new opportunities for the treatment […]

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'Terminal cancer diagnosis made me feel nothing but gratitude for life I've had'

Doreen was diagnosed with stage 4 lung cancer four years ago – there is no cure. The cancer had already spread to Doreen’s brain by the time it was detected, but the 70-year-old has taken the diagnosis in her stride, literally. A passionate long-distance walker, Doreen feels grateful that she is still able to keep active and says that walking […]

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Study examines genetic testing in diverse young breast cancer patients over a decade

Breast cancer patients diagnosed under age 50 represent 18 percent of new invasive breast cancer cases in the United States. Compared to postmenopausal women, younger women are more likely to develop aggressive subtypes of breast cancer, have a worse prognosis with increased risk of recurrence, and have higher overall mortality. Young breast cancer patients also are more likely to be […]

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Select few cancer patients enroll in potentially life-extending clinical trials

Patient enrollment in clinical trials as the first course of treatment after cancer diagnosis is low, despite the fact that enrollment may increase life expectancy, according to researchers at Penn State. They also found that white males with private health insurance and metastatic cancers treated at academic medical centers are more likely than other groups to enroll in clinical trials. […]

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Blood-clotting protein and blood platelets promote immune evasion, cancer progression

A new study led by researchers at The Ohio State University Comprehensive Cancer Center—Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC—James) reveals how a clotting protein and blood platelets can promote cancer progression and suppress immune responses to cancer. The findings show how thrombin, a clotting protein in the blood, causes blood platelets to release transforming […]

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