FDA Approves Trodelvy, the First Treatment for Metastatic Triple-Negative Breast Cancer Shown to Improve Progression-Free Survival and Overall Survival

FOSTER CITY, Calif.–(BUSINESS WIRE)–Apr. 7, 2021– Gilead Sciences, Inc. (Nasdaq: GILD) today announced that the U.S. Food and Drug Administration (FDA) has granted full approval to Trodelvy® (sacituzumab govitecan-hziy) for adult patients with unresectable locally advanced or metastatic triple-negative breast cancer (TNBC) who have received two or more prior systemic therapies, at least one of them for metastatic disease. The approval is supported by data […]

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Alternative cancer cell fuel source targeted as therapeutic approach for breast cancer

Scientists at The Wistar Institute characterized an inhibitor that targets acetate metabolism in cancer cells. Cancer cells use acetate metabolism to support tumor growth in conditions of low nutrient and oxygen availability. This molecule caused tumor growth inhibition and regression in preclinical studies, demonstrating the promise of this approach as a novel therapeutic strategy for solid tumors. Study results were […]

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Statins may protect the heart from chemotherapy treatment of early breast cancer

Statins, common cholesterol-lowering medications, may protect women’s hearts from damage caused during chemotherapy for early-stage breast cancer, according to new research published today in the Journal of the American Heart Association. “Two types of cancer medications, anthracyclines and trastuzumab, are effective treatments for many women with breast cancer, however, the risk of heart muscle damage has limited their use, particularly […]

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SABCS: Some Older Women With Breast Cancer May Opt to Skip RT

MONDAY, Dec. 14, 2020 — The omission of radiotherapy (RT) does not affect overall survival at 10 years after breast conserving surgery (BCS) for older women with hormone receptor-positive breast cancer, according to a study presented at the annual San Antonio Breast Cancer Symposium, held virtually from Dec. 8 to 11. Ian H. Kunkler, from the University of Edinburgh in […]

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Many Male Breast Cancers Diagnosed Late, and Delays Can Be Lethal

THURSDAY, Oct. 15, 2020 — Breast cancer in men is rare. But because it’s not often suspected in men, diagnosis often comes only after a tumor has begun to spread throughout the body, new research shows. “Approximately one-half of males with breast cancer received a diagnosis after it had already spread,” either to nearby or distant tissues, said a team […]

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Breast cancer drug set to transform prostate cancer treatment

A drug used to treat breast and ovarian cancer can extend the lives of some men with prostate cancer and should become a new standard treatment for the disease, concludes a major trial which is set to change clinical practice. Final results from the trial showed that olaparib—a pioneering type of drug called a PARP inhibitor and the first ever […]

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