Discovery of blood biomarker opens new perspectives for dietary prevention of AMD-related risks

Age-related macular degeneration (AMD) is the principal cause of vision loss in industrialized countries, with nearly 20 million people affected in Europe in 2020. Although identified as a risk factor, until now it was impossible to evaluate retinal omega-3 fatty acid deficits. A research team involving scientists from INRAE, INSERM, Université Jean-Monnet Saint-Etienne, Université de Bordeaux, ITERG and Dijon-Bourgogne and […]

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Study evaluates biomarker criteria for assessing Alzheimer’s risk

One of the biggest challenges in Alzheimer’s research is to identify biomarkers that can identify people who are at risk of developing dementia. Biomarkers could be used to screen people so they might be helped before they develop dementia. Researchers have focused primarily on three such biomarkers. Two are Alzheimer’s-related proteins, amyloid and tau. Amyloid forms clumps in brains, and […]

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Oral Microbiome Linked to COVID-19 Diagnosis

NEW YORK (Reuters Health) – Oral microbial markers may be a potential diagnostic tool for COVID-19, researchers suggest. As reported in Gut, Dr. Lanjuan Li of Zhengzhou University in China and colleagues sequenced 392 tongue-coating samples, 172 fecal and 155 serum samples from Central and East China. They characterized the microbiome and lipid molecules, then constructed microbial classifiers in a […]

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Newly identified biomarker could predict response to immune checkpoint inhibitors

A team of Roswell Park Comprehensive Cancer Center researchers has identified a new biomarker that could predict response to immune checkpoint inhibitors (ICI) shortly after patients with non-small cell lung cancer (NSCLC) initiate therapy. This discovery, published today in the journal Nature Communications, is not only an important step forward in lung cancer treatment, but also has implications for other […]

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Point-of-care biomarker assay for traumatic brain injury

Intracranial abnormalities on CT scan in patients with traumatic brain injury (TBI) can be predicted by glial fibrillary acidic protein (GFAP) levels in the blood. These interim findings from the TRACK-TBI study are published in the peer-reviewed Journal of Neurotrauma. GFAP’s diagnostic performance was significantly better than that of the S100B biomarker, to which it was compared. S100B is approved […]

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Study shows biomarker accurately diagnoses deadly infant disease

A diagnostic study of 136 premature infants found that a protein involved in managing harmful bacteria in the human intestine is a reliable biomarker for the noninvasive detection of necrotizing enterocolitis (NEC). Led by researchers and clinicians at LSU Health New Orleans School of Medicine, this is one of the largest prospective clinical studies in premature infants yet. Results of […]

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Scientists develop a physical biomarker for cornea restoration therapy

Our eyes—the windows to the soul—need constant care, and as we age, they sometimes also need significant repair. The panes of these windows—the corneas—are transparent tissues that have been the focus of some of the oldest and most common transplantation surgeries. Now thanks to researchers in Kyoto, some such transplants may become even safer. The team, led by Kyoto University […]

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