ASCO Esophageal Cancer Guidance Updated to Include Nivolumab

Patients with locally advanced esophageal cancer who have residual disease following chemoradiotherapy (CRT) and surgery should be offered nivolumab (Opdivo), says a rapid update to American Society of Clinical Oncology (ASCO) guidance. This could transform the treatment of “about 75%” of patients with ongoing disease despite CRT and surgery, co-author of the guidelines update, Wayne L. Hofstetter, MD, University of […]

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FDA Revokes Emergency Use of Solo Bamlanivimab for COVID

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. The US Food and Drug Administration (FDA) has granted Eli Lilly’s request to revoke emergency use authorization for the COVID-19 monoclonal antibody therapy bamlanivimab when used as a monotherapy, saying the evidence indicates that it is likely not effective against currently circulating variants. The agency said in […]

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COVID-19 Vaccination in RMD Patients: Safety Data ‘Reassuring’

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Two reports support the safety and immunogenicity of SARS-CoV-2 mRNA vaccines in patients with rheumatic and musculoskeletal diseases (RMDs) and represent the first available data on such patients. In an observational cohort study published in Annals of the Rheumatic Diseases, Caoilfhionn M. Connolly, MD, of Johns Hopkins […]

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